Gene Symbol: mapk10
Description: mitogen-activated protein kinase 10
Alias: zgc:123234, mitogen-activated protein kinase 10, jnk3
Seo J, Asaoka Y, Nagai Y, Hirayama J, Yamasaki T, Namae M, et al
. Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation. J Cell Biochem. 2010;110:1022-37 pubmed publisher
..Furthermore, non-canonical Wnt signaling may coordinate vertebrate CE movements by triggering Jnk activation that represses the expression of the CE-triggering ligand wnt11. ..
Drerup C, Nechiporuk A. JNK-interacting protein 3 mediates the retrograde transport of activated c-Jun N-terminal kinase and lysosomes. PLoS Genet. 2013;9:e1003303 pubmed publisher
..Furthermore, our data provide strong evidence that Jip3 in fact serves as an adapter protein linking these cargos to dynein...
Liu L, Fox C, North T, Goessling W. Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development. Dis Model Mech. 2013;6:1271-8 pubmed publisher
..Knockdown of three genes (pnpla3, pklr and mapk10) decreased expression of hepatic progenitor cells, whereas knockdown of eight genes (pnpla3, cpn1, trib1, fads2, ..
Gautier A, Le Gac F, Lareyre J. The gsdf gene locus harbors evolutionary conserved and clustered genes preferentially expressed in fish previtellogenic oocytes. Gene. 2011;472:7-17 pubmed publisher
..Interestingly, our study identifies new clustered genes that are specifically expressed in previtellogenic oocytes (nup54, aff1, klhl8, sdad1). ..
Encinas P, Garcia Valtanen P, Chinchilla B, Gomez Casado E, Estepa A, Coll J. Identification of multipath genes differentially expressed in pathway-targeted microarrays in zebrafish infected and surviving spring viremia carp virus (SVCV) suggest preventive drug candidates. PLoS ONE. 2013;8:e73553 pubmed publisher
..These results could contribute to develop novel drug-based prevention methods and consolidate the zebrafish/SVCV as a model for vertebrate viral diseases. ..
Heanue T, Boesmans W, Bell D, Kawakami K, Vanden Berghe P, Pachnis V. A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity. PLoS Genet. 2016;12:e1006439 pubmed publisher
..We generated mapk10 loss-of-function mutants, which show reduced numbers of enteric neurons...