large2

Summary

Gene Symbol: large2
Description: LARGE xylosyl- and glucuronyltransferase 2
Alias: gyltl1b, si:ch211-206g24.1, si:ch211-282n12.1, LARGE xylosyl- and glucuronyltransferase 2, glycosyltransferase-like 1b, glycosyltransferase-like protein LARGE2
Species: zebrafish

Top Publications

  1. Grewal P, McLaughlan J, Moore C, Browning C, Hewitt J. Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies. Glycobiology. 2005;15:912-23 pubmed
    ..Hence, they are termed dystroglycanopathies. A paralogous gene for LARGE (LARGE2 or GYLTL1B) may also have a role in DG glycosylation...
  2. Moore C, Goh H, Hewitt J. Genes required for functional glycosylation of dystroglycan are conserved in zebrafish. Genomics. 2008;92:159-67 pubmed publisher
    ..In contrast, Large2 expression is more restricted and by 30 hpf is confined to the lens, cerebellum, and pronephric duct...