Gene Symbol: lamp1b
Description: lysosomal associated membrane protein 1b
Alias: fa56f11, lamp1, si:ch211-218d20.14, wu:fa56f11, lysosomal-associated membrane protein 1, lysosome-associated membrane glycoprotein 1-like
Roostalu U, Strahle U. In vivo imaging of molecular interactions at damaged sarcolemma. Dev Cell. 2012;22:515-29 pubmed publisher
..Thus, sarcolemmal repair relies on the ordered assembly of a protein-membrane scaffold. Moreover, we provide several lines of evidence that the membrane for sarcolemmal repair is derived from a specialized plasma membrane compartment. ..
Ellis K, Bagwell J, Bagnat M. Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis. J Cell Biol. 2013;200:667-79 pubmed publisher
..Thus, the vertebrate notochord plays important structural roles beyond early development...
Drerup C, Nechiporuk A. JNK-interacting protein 3 mediates the retrograde transport of activated c-Jun N-terminal kinase and lysosomes. PLoS Genet. 2013;9:e1003303 pubmed publisher
..Furthermore, our data provide strong evidence that Jip3 in fact serves as an adapter protein linking these cargos to dynein...
Rengarajan C, Matzke A, Reiner L, Orian Rousseau V, Scholpp S. Endocytosis of Fgf8 is a double-stage process and regulates spreading and signaling. PLoS ONE. 2014;9:e86373 pubmed publisher
..Therefore, we hypothesize that Fgf8 receiving cells control both, the propagation width and the signal strength of the morphogen...
Biga P, Latimer M, Froehlich J, Gabillard J, Seiliez I. Distribution of H3K27me3, H3K9me3, and H3K4me3 along autophagy-related genes highly expressed in starved zebrafish myotubes. Biol Open. 2017;6:1720-1725 pubmed publisher
..These data support epigenetic regulation of autophagy in response to starvation that suggests a level of regulation that can be sustained for chronic conditions via chromatin modification. ..
Yoder J, Orcutt T, Traver D, Litman G. Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 2007;401:154-64 pubmed
..Their genomic organizations have been characterized, cDNA transcripts have been recovered, phylogenetic relationships have been defined and their cell lineage-specific expression patterns have been established. ..
Sonal -, Sidhaye J, Phatak M, Banerjee S, Mulay A, Deshpande O, et al
. Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis. PLoS Genet. 2014;10:e1004614 pubmed publisher
..Our analyses unravel the importance of Myosin Vb dependent cell size regulation in epidermal homeostasis and demonstrate that the epidermis has the ability to maintain a dynamic balance between cell size and cell number. ..
Rasmussen J, Sack G, Martin S, Sagasti A. Vertebrate epidermal cells are broad-specificity phagocytes that clear sensory axon debris. J Neurosci. 2015;35:559-70 pubmed publisher
..Together, these results identify vertebrate epidermal cells as broad-specificity phagocytes that likely contribute to neural repair and wound healing. ..
Yu S, Li C, Biswas L, Hu X, Liu F, Reilly J, et al
. CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish. Hum Mol Genet. 2017;26:2335-2345 pubmed publisher
..We conclude that CERKL deficiency in zebrafish may cause rod-cone dystrophy, but not cone-rod dystrophy, while interfering with the phagocytosis function of RPE associated with down-regulation of the expression of MERTK. ..