Gene Symbol: klf4
Description: Kruppel-like factor 4
Alias: klf4a, Krueppel-like factor 4, Kruppel-like factor 4a, Kruppel-like transcription factor 4a
Species: zebrafish

Top Publications

  1. Li I, Chan C, Lu Y, Wu Y, Chen Y, Li G, et al. Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages. PLoS ONE. 2011;6:e20974 pubmed publisher
    ..We characterized the function of klf4a, a mammalian klf4 homologue by antisense morpholino oligomer knockdown...
  2. Just S, Berger I, Meder B, Backs J, Keller A, Marquart S, et al. Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity. Circulation. 2011;124:324-34 pubmed publisher
    ..We demonstrate for the first time that proper heart valve formation critically depends on Protein kinase D2-Histone deacetylase 5-Krüppel-like factor signaling. ..
  3. Andersen I, Reiner A, Aanes H, Alestrom P, Collas P. Developmental features of DNA methylation during activation of the embryonic zebrafish genome. Genome Biol. 2012;13:R65 pubmed publisher
  4. Rossell R, Chen C, Dai R, Howard J, Hochgeschwender U, Jarvis E. Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species. elife. 2013;2:e00036 pubmed publisher
    ..We suggest that the stem-cell state may be highly conserved across a wide phylogenetic range. DOI:http://dx.doi.org/10.7554/eLife.00036.001...
  5. Akhter A, Kumagai R, Roy S, Ii S, Tokumoto M, Hossain B, et al. Generation of Transparent Zebrafish with Fluorescent Ovaries: A Living Visible Model for Reproductive Biology. Zebrafish. 2016;13:155-60 pubmed publisher
    ..We identified a fluorescent tissue that might contain the undifferentiated germ cells close to the cloaca in the strain. This strain can be used for analysis of ovarian development in vivo. ..
  6. Shao M, Ge G, Liu W, Xiao J, Xia H, Fan Y, et al. Characterization and phylogenetic analysis of Krüppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis). Oncotarget. 2017;8:16325-16339 pubmed publisher
    ..TbKLF5, like hKLF5, significantly promotes NIH3T3 cell proliferation in vitro. These results provide insight for future studies regarding the structure and function of the tbKLF gene family. ..
  7. Lush M, Piotrowski T. ErbB expressing Schwann cells control lateral line progenitor cells via non-cell-autonomous regulation of Wnt/?-catenin. elife. 2014;3:e01832 pubmed publisher
    ..DOI: http://dx.doi.org/10.7554/eLife.01832.001. ..
  8. Novodvorsky P, Watson O, Gray C, Wilkinson R, Reeve S, Smythe C, et al. klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. PLoS ONE. 2015;10:e0141611 pubmed publisher
    ..We detected vascular expression of klf2b (but not klf4a or biklf/klf4b/klf17) in wildtypes but found no differences in expression that might account for the lack of ..
  9. Fan Z, Liu L, Huang X, Zhao Y, Zhou L, Wang D, et al. Establishment and growth responses of Nile tilapia embryonic stem-like cell lines under feeder-free condition. Dev Growth Differ. 2017;59:83-93 pubmed publisher
    ..activity and expression of pluripotency genes including pou5f3 (the pou5f1/oct4 homologue), sox2, myc and klf4. In suspension culture together with retinoic acid treatment, TES1 cells formed embryoid bodies, which exhibited ..