Gene Symbol: kitlgb
Description: kit ligand b
Alias: kitlb, kit ligand b
Species: zebrafish

Top Publications

  1. Hultman K, Bahary N, Zon L, Johnson S. Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a. PLoS Genet. 2007;3:e17 pubmed
    ..the partitioning of expression patterns and functions of two zebrafish kit ligands, kit ligand a (kitla) and kit ligand b (kitlb), and discuss their possible coevolution with the duplicated zebrafish kit receptors (kita and kitb)...
  2. Yao K, Ge W. Kit system in the zebrafish ovary: evidence for functional divergence of two isoforms of kit (kita and kitb) and kit ligand (kitlga and kitlgb) during folliculogenesis. Biol Reprod. 2010;82:1216-26 pubmed publisher
    ..Unlike mammalian species, two copies of genes are present in the zebrafish genome for both ligand (kitlga and kitlgb) and receptor (kita and kitb)...
  3. Morais R, Crespo D, Nóbrega R, Lemos M, van de Kant H, De Franca L, et al. Antagonistic regulation of spermatogonial differentiation in zebrafish (Danio rerio) by Igf3 and Amh. Mol Cell Endocrinol. 2017;454:112-124 pubmed publisher
    ..Our data suggest that an important aspect of Fsh bioactivity in stimulating spermatogenesis is implemented by restricting the different inhibitory effects of Amh and by counterbalancing them with stimulatory signals, such as Igf3. ..
  4. Rich A, Leddon S, Hess S, Gibbons S, Miller S, Xu X, et al. Kit-like immunoreactivity in the zebrafish gastrointestinal tract reveals putative ICC. Dev Dyn. 2007;236:903-11 pubmed
    ..designed to amplify mRNA coding for two zebrafish kit genes, kita and kitb, and two kit ligands, kitla and kitlb, amplified the expected transcript from total RNA isolated from zebrafish GI tissues...
  5. Yao K, Ge W. Spatial distribution and receptor specificity of zebrafish Kit system--evidence for a Kit-mediated bi-directional communication system in the preovulatory ovarian follicle. PLoS ONE. 2013;8:e56192 pubmed publisher
    ..In the zebrafish, the Kit system contains two ligands (Kitlga and Kitlgb) and two receptors (Kita and Kitb)...
  6. Mahony C, Fish R, Pasche C, Bertrand J. tfec controls the hematopoietic stem cell vascular niche during zebrafish embryogenesis. Blood. 2016;128:1336-45 pubmed publisher
    ..Among these, we found kitlgb, which could rescue the loss of HSCs observed in tfec mutants...