Genomes and Genes

Species

Gene Symbol: kcnk3a

Description: potassium channel, subfamily K, member 3a

Alias: kcnk3, si:dkey-164m15.1, potassium channel subfamily K member 3, potassium channel, subfamily K, member 3

Species: zebrafish

Gierten J, Hassel D, Schweizer P, Becker R, Katus H, Thomas D. Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels. Biochim Biophys Acta. 2012;1818:33-41 pubmed publisher

..1 two-pore-domain K(+) channels that exhibit structural and functional properties largely similar to human K(2P)10.1. We conclude that the zebrafish represents a valid model to study K(2P)10.1 function in vivo. ..
Liang B, Soka M, Christensen A, Olesen M, Larsen A, Knop F, et al. Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis. J Mol Cell Cardiol. 2014;67:69-76 pubmed publisher

..To address these questions, we first evaluated the effects of transient knockdown of the zebrafish kcnk3a and kcnk3b genes and cardiac phenotypes were evaluated using videomicroscopy...