Gene Symbol: itpr2
Description: inositol 1,4,5-trisphosphate receptor, type 2
Alias: si:dkey-196d8.1, inositol 1,4,5-trisphosphate receptor type 2, inositol 1,4,5-triphosphate receptor, type 2
Species: zebrafish
Products:     itpr2

Top Publications

  1. Paavola J, Schliffke S, Rossetti S, Kuo I, Yuan S, Sun Z, et al. Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy. J Mol Cell Cardiol. 2013;58:199-208 pubmed publisher
    ..In human subjects we found an association between ADPKD and IDCM and suggest that PKD mutations contribute to the development of heart failure. ..
  2. Ashworth R, Devogelaere B, Fabes J, Tunwell R, Koh K, De Smedt H, et al. Molecular and functional characterization of inositol trisphosphate receptors during early zebrafish development. J Biol Chem. 2007;282:13984-93 pubmed
    ..Inhibition of Ca(2+) entry or ryanodine receptors, however, had little effect. Our work defines the importance of IP(3) receptors during early development of a genetically and optically tractable model vertebrate organism. ..

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