itpr1a

Summary

Gene Symbol: itpr1a
Description: inositol 1,4,5-trisphosphate receptor, type 1a
Alias: inositol 1,4,5-trisphosphate receptor type 1, ITPR1b1, ITPR1b3, inositol 1,4,5-triphosphate receptor, type 1a
Species: zebrafish

Top Publications

  1. Ashworth R, Devogelaere B, Fabes J, Tunwell R, Koh K, De Smedt H, et al. Molecular and functional characterization of inositol trisphosphate receptors during early zebrafish development. J Biol Chem. 2007;282:13984-93 pubmed
    ..Inhibition of Ca(2+) entry or ryanodine receptors, however, had little effect. Our work defines the importance of IP(3) receptors during early development of a genetically and optically tractable model vertebrate organism. ..
  2. Aspatwar A, Tolvanen M, Jokitalo E, Parikka M, Ortutay C, Harjula S, et al. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish. Hum Mol Genet. 2013;22:417-32 pubmed publisher
    ..This work reveals an evolutionarily conserved function of CARP VIII in brain development and introduces a novel zebrafish model in which to investigate the mechanisms of CARP VIII-related ataxia and mental retardation in humans...