Gene Symbol: irx4b
Description: iroquois homeobox 4b
Alias: ziro4b, iroquois-class homeodomain protein IRX-4, iroquois homeobox protein 4b
Species: zebrafish

Top Publications

  1. Lecaudey V, Anselme I, Dildrop R, Ruther U, Schneider Maunoury S. Expression of the zebrafish Iroquois genes during early nervous system formation and patterning. J Comp Neurol. 2005;492:289-302 pubmed
    ..Overall, these expression data suggest functions for the Iroquois family of transcription factors in neural and placodal patterning, neurogenesis, and neuronal specification. ..
  2. Feijóo C, Manzanares M, de la Calle Mustienes E, Gomez Skarmeta J, Allende M. The Irx gene family in zebrafish: genomic structure, evolution and initial characterization of irx5b. Dev Genes Evol. 2004;214:277-84 pubmed
    ..In total there are 11 existing Irx genes in zebrafish and 10 in pufferfish. We propose a new nomenclature for the zebrafish Irx genes based on the analysis of their sequences and their genomic relationships. ..
  3. McDonald L, Gerrelli D, Fok Y, Hurst L, Tickle C. Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos. J Anat. 2010;216:683-91 pubmed publisher
    ..In zebrafish, Irx genes of all but six of the families are expressed in early stage pectoral fin buds but not at later stages, suggesting that these genes are not involved in patterning distal structures in zebrafish fins. ..
  4. Mullally M, Albrecht C, Horton M, Laboissonniere L, Goetz J, Chowdhury R, et al. Expression Profiling of Developing Zebrafish Retinal Cells. Zebrafish. 2016;13:272-80 pubmed publisher
    ..Further analysis of these profiles will reveal genes that can be mutated using genome editing techniques. Together these studies increase our knowledge of the genes driving development of different cell types in the zebrafish retina. ..