Gene Symbol: irf5
Description: interferon regulatory factor 5
Alias: im:7155364, zgc:76986, interferon regulatory factor 5
Xu Q, Chang M, Xiao F, Huang B, Nie P. The gene and virus-induced expression of IRF-5 in grass carp Ctenopharyngodon idella. Vet Immunol Immunopathol. 2010;134:269-78 pubmed publisher
The interferon regulatory factor 5 (IRF-5) is known to be involved in the innate immune response and in the regulation of DNA damage-induced apoptosis...
Shan S, Qi C, Zhu Y, Li H, An L, Yang G. Expression profile of carp IFN correlate with the up-regulation of interferon regulatory factor-1 (IRF-1) in vivo and in vitro: the pivotal molecules in antiviral defense. Fish Shellfish Immunol. 2016;52:94-102 pubmed publisher
..Furthermore, we also isolate the peripheral blood leukocytes (PBLs) and find that there is a relevance between the expression profile of CcIRF-1 and IFN in poly(I:C) stimulated PBLs. ..
Ai K, Luo K, Li Y, Hu W, Gao W, Fang L, et al
. Expression pattern analysis of IRF4 and its related genes revealed the functional differentiation of IRF4 paralogues in teleost. Fish Shellfish Immunol. 2017;60:59-64 pubmed publisher
..It can regulate immune pathway through IRF5, MyD88, IL21, PGC1?, and NOD2...
Qiu X, Lv M, Jian X, Chen D, Zhou H, Zhang A, et al
. In vitro characterization of grass carp (Ctenopharyngodon idella) IL-26 in regulating inflammatory factors. Fish Shellfish Immunol. 2017;66:148-155 pubmed publisher
..Those results collectively demonstrated the functional role of IL-26 in regulating inflammatory response in fish. ..
Huang B, Qi Z, Xu Z, Nie P. Global characterization of interferon regulatory factor (IRF) genes in vertebrates: glimpse of the diversification in evolution. BMC Immunol. 2010;11:22 pubmed publisher
..However, the ten IRF family members in vertebrates and those IRF-like genes in non-vertebrate deuterostomes were quite different in those analyzed characters, as they might have undergone different patterns of evolution. ..
Xiang Z, Dong C, Qi L, Chen W, Huang L, Li Z, et al
. Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio). Dev Comp Immunol. 2010;34:1263-73 pubmed publisher
..We suggest that zfIRF5 is a new kind of splicing variant, following the nine other kinds of IRF5 splicing variants found in mammals...
Tong C, Zhang C, Zhang R, Zhao K. Transcriptome profiling analysis of naked carp (Gymnocypris przewalskii) provides insights into the immune-related genes in highland fish. Fish Shellfish Immunol. 2015;46:366-77 pubmed publisher