Gene Symbol: irf10
Description: interferon regulatory factor 10
Alias: zgc:76891, interferon regulatory factor 10
Li S, Lu L, Feng H, Wu N, Chen D, Zhang Y, et al
. IFN regulatory factor 10 is a negative regulator of the IFN responses in fish. J Immunol. 2014;193:1100-9 pubmed publisher
..have been identified as critical regulators in the IFN responses in both fish and mammals; however, the role of IRF10 is unclear...
Shan S, Qi C, Zhu Y, Li H, An L, Yang G. Expression profile of carp IFN correlate with the up-regulation of interferon regulatory factor-1 (IRF-1) in vivo and in vitro: the pivotal molecules in antiviral defense. Fish Shellfish Immunol. 2016;52:94-102 pubmed publisher
..Furthermore, we also isolate the peripheral blood leukocytes (PBLs) and find that there is a relevance between the expression profile of CcIRF-1 and IFN in poly(I:C) stimulated PBLs. ..
Huang B, Qi Z, Xu Z, Nie P. Global characterization of interferon regulatory factor (IRF) genes in vertebrates: glimpse of the diversification in evolution. BMC Immunol. 2010;11:22 pubmed publisher
..However, the ten IRF family members in vertebrates and those IRF-like genes in non-vertebrate deuterostomes were quite different in those analyzed characters, as they might have undergone different patterns of evolution. ..
Suzuki Y, Yasuike M, Kondo H, Aoki T, Hirono I. Molecular cloning and expression analysis of interferon regulatory factor 10 (IRF10) in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2011;30:67-76 pubmed publisher
Interferons (IFNs) are important for the defense against intracellular pathogens. Interferon regulatory factor 10 (IRF10) is a transcript factor involved in regulating IFN signaling induced by virus infections in birds, but little is ..
Ai K, Luo K, Li Y, Hu W, Gao W, Fang L, et al
. Expression pattern analysis of IRF4 and its related genes revealed the functional differentiation of IRF4 paralogues in teleost. Fish Shellfish Immunol. 2017;60:59-64 pubmed publisher
..01). IRF4a and IRF4b displayed a distinct tissue expression pattern, embryonic stages expression and inducible expression in vivo and in vitro, suggesting that IRF4 paralogues might play different roles in immune system. ..