Gene Symbol: impdh1a
Description: IMP (inosine 5'-monophosphate) dehydrogenase 1a
Alias: IMPD 1a, IMPDH 1a, zgc:91911, inosine-5'-monophosphate dehydrogenase 1a, inosine 5'-phosphate dehydrogenase 1a
Species: zebrafish
Products:     impdh1a

Top Publications

  1. Li Y, Li G, Görling B, Luy B, Du J, Yan J. Integrative analysis of circadian transcriptome and metabolic network reveals the role of de novo purine synthesis in circadian control of cell cycle. PLoS Comput Biol. 2015;11:e1004086 pubmed publisher
    ..impdh), a rate-limiting enzyme in de novo purine synthesis, with three circadian oscillating gene homologs: impdh1a, impdh1b and impdh2...
  2. Jiang L, Liu M, Li J, He Z, Li H, Shen N, et al. Mycophenolic Acid-Induced Developmental Defects in Zebrafish Embryos. Int J Toxicol. 2016;35:712-718 pubmed
    ..3 µmol/L guanosine. Our results indicated that MPA impairs the development of zebrafish embryos via inhibition of impdh activity, which subsequently caused a guanosine nucleotide depletion in vivo. ..

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