Gene Symbol: il6r
Description: interleukin 6 receptor
Alias: il-6ra, interleukin-6 receptor subunit alpha, interleukin 6 receptor alpha
Varela M, Dios S, Novoa B, Figueras A. Characterisation, expression and ontogeny of interleukin-6 and its receptors in zebrafish (Danio rerio). Dev Comp Immunol. 2012;37:97-106 pubmed publisher
Sanden M, Jørgensen S, Hemre G, Ørnsrud R, Sissener N. Zebrafish (Danio rerio) as a model for investigating dietary toxic effects of deoxynivalenol contamination in aquaculture feeds. Food Chem Toxicol. 2012;50:4441-8 pubmed publisher
..We do not know if effects observed on fecundity and larvae swimming activity are attributed to a direct interaction of DON with the reproductive organ or secondary to the maternal/paternal liver oxidative imbalance. ..
Lim S, Esain V, Kwan W, Theodore L, Cortes M, Frost I, et al
. HIF1?-induced PDGFR? signaling promotes developmental HSC production via IL-6 activation. Exp Hematol. 2017;46:83-95.e6 pubmed publisher
..Together, these findings define a Hif1?-regulated signaling axis mediated through PBFGB/PDGFR? and IL-6/IL-6R that acts to control embryonic HSPC production. ..
Rovira M, Arrey G, Planas J. Exercise-Induced Hypertrophic and Oxidative Signaling Pathways and Myokine Expression in Fast Muscle of Adult Zebrafish. Front Physiol. 2017;8:1063 pubmed publisher
..The mRNA expression levels of il6, il6r, apln, aplnra and aplnrb, sparc, decorin and igf1, myokines known in mammals to be produced in ..
Zhang H, Fei C, Wu H, Yang M, Liu Q, Wang Q, et al
. Transcriptome profiling reveals Th17-like immune responses induced in zebrafish bath-vaccinated with a live attenuated Vibrio anguillarum. PLoS ONE. 2013;8:e73871 pubmed publisher
..The transcriptome profiling with microarray revealed the Th17-like immune response to bath-vaccination with the live attenuated V. anguillarum in zebrafish. ..
Zhao X, Wan J, Powell C, Ramachandran R, Myers M, Goldman D. Leptin and IL-6 family cytokines synergize to stimulate Müller glia reprogramming and retina regeneration. Cell Rep. 2014;9:272-284 pubmed publisher
..Our study not only furthers our understanding of retina regeneration in zebrafish but also suggests new strategies for awakening retina regeneration in mammals. ..