Gene Symbol: idh2
Description: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Alias: wu:fb33c06, wu:fk31e05, wu:fq43b01, zgc:55485, isocitrate dehydrogenase [NADP], mitochondrial
Species: zebrafish
Products:     idh2

Top Publications

  1. Gebriel M, Prabhudesai S, Uleberg K, Larssen E, Piston D, Bjørnstad A, et al. Zebrafish brain proteomics reveals central proteins involved in neurodegeneration. J Neurosci Res. 2014;92:104-15 pubmed publisher
  2. Chun H, Shin S, Ahn S, Shin D, Choi S, Ahn J, et al. KR-62980 suppresses lipid metabolism through inhibition of cytosolic NADP isocitrate dehydrogenase in zebrafish. Zebrafish. 2014;11:122-8 pubmed publisher
    ..Further, KR-62980 substantially suppressed cICDH in adipocytes and zebrafish. These results suggest that cICDH may be one of the targets of KR-62980 responsible for weight gain and adipogenesis. ..
  3. Gündel U, Kalkhof S, Zitzkat D, von Bergen M, Altenburger R, Küster E. Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome. Ecotoxicol Environ Saf. 2012;76:11-22 pubmed publisher
    ..Using this experimental design based on testing of several exposure concentrations and less replicates might provide a step forward in getting increased output from toxicoproteomics studies. ..
  4. Holowiecki A, O Shields B, Jenny M. Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress. Comp Biochem Physiol C Toxicol Pharmacol. 2017;191:138-151 pubmed publisher
    ..Together, these data suggest that Gata-1 and Nrf2a play differential roles in regulating the heme degradation enzymes during an early developmental period of heightened cellular stress. ..