id2a

Summary

Gene Symbol: id2a
Description: inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a
Alias: cb321, id2, wu:fa04e03, DNA-binding protein inhibitor ID-2
Species: zebrafish

Top Publications

  1. ncbi Zebrafish id2 developmental expression pattern contains evolutionary conserved and species-specific characteristics
    Shang Wei Chong
    Laboratory of Fish Developmental Biology, Institute of Molecular and Cell Biology, National University of Singapore
    Dev Dyn 234:1055-63. 2005
  2. ncbi Differential expression and regulation of olig genes in zebrafish
    Natascia Tiso
    Department of Biology, University of Padova, I 35131 Padova, Italy
    J Comp Neurol 515:378-96. 2009
  3. ncbi Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics
    Rosa A Uribe
    Section of Molecular Cell and Developmental Biology, Institute for Cell and Molecular Biology, The University of Texas at Austin, Austin, TX 78722, USA
    Development 137:3763-74. 2010
  4. ncbi Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein
    David M Wiley
    Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nat Cell Biol 13:686-92. 2011
  5. ncbi Discovery and assessment of conserved Pax6 target genes and enhancers
    Pedro Coutinho
    Medical Research Council MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
    Genome Res 21:1349-59. 2011
  6. ncbi Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish
    Joanie C Neumann
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proc Natl Acad Sci U S A 108:13153-8. 2011

Scientific Experts

  • N Tiso
  • Pedro Coutinho
  • Joanie C Neumann
  • David M Wiley
  • Rosa A Uribe
  • Shang Wei Chong
  • Vanessa A Damoulis
  • Nicholas J Fustino
  • Katherine Lillard
  • James F Amatruda
  • Garvin L Chandler
  • Victoria L Bautch
  • Jijun Hao
  • Dinesh Rakheja
  • Linda Margraf
  • Suk Won Jin
  • Charles C Hong
  • Leendert Looijenga
  • Jun Dae Kim
  • Jeffrey M Gross
  • Thi-Thu-Hang Nguyen
  • Thi Thu Hang Nguyen
  • Lee Thean Chu
  • Lee-Thean Chu
  • Yun Jin Jiang
  • Yun-Jin Jiang
  • Shang-Wei Chong
  • Vladimir Korzh

Detail Information

Publications6

  1. ncbi Zebrafish id2 developmental expression pattern contains evolutionary conserved and species-specific characteristics
    Shang Wei Chong
    Laboratory of Fish Developmental Biology, Institute of Molecular and Cell Biology, National University of Singapore
    Dev Dyn 234:1055-63. 2005
    ..We isolated zebrafish id2, and its expression during development was characterized...
  2. ncbi Differential expression and regulation of olig genes in zebrafish
    Natascia Tiso
    Department of Biology, University of Padova, I 35131 Padova, Italy
    J Comp Neurol 515:378-96. 2009
    ..Our findings suggest a role for olig genes in CNS patterning as well as in multiple cell fate decisions during neural differentiation...
  3. ncbi Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics
    Rosa A Uribe
    Section of Molecular Cell and Developmental Biology, Institute for Cell and Molecular Biology, The University of Texas at Austin, Austin, TX 78722, USA
    Development 137:3763-74. 2010
    ..Using loss-of-function and overexpression assays in zebrafish, we demonstrate that Id2a levels modulate retinoblast cell cycle kinetics and thereby influence neuron and glia formation in the retina...
  4. ncbi Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein
    David M Wiley
    Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nat Cell Biol 13:686-92. 2011
    ....
  5. ncbi Discovery and assessment of conserved Pax6 target genes and enhancers
    Pedro Coutinho
    Medical Research Council MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
    Genome Res 21:1349-59. 2011
    ..We have identified several novel direct targets, including some putative disease genes, among them Foxp2; these will allow further dissection of Pax6 function in development and disease...
  6. ncbi Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish
    Joanie C Neumann
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proc Natl Acad Sci U S A 108:13153-8. 2011
    ..These results indicate a germ-cell-autonomous role for BMP signal transduction in germ-cell differentiation, and highlight the importance of the BMP pathway in human GCTs...