hspg2

Summary

Gene Symbol: hspg2
Description: heparan sulfate proteoglycan 2
Alias: basement membrane-specific heparan sulfate proteoglycan core protein, perlecan
Species: zebrafish

Top Publications

  1. Holmborn K, Habicher J, Kasza Z, Eriksson A, Filipek Gorniok B, Gopal S, et al. On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. J Biol Chem. 2012;287:33905-16 pubmed
  2. Zoeller J, Whitelock J, Iozzo R. Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. Matrix Biol. 2009;28:284-91 pubmed publisher
    Using the zebrafish, we previously identified a central function for perlecan during angiogenic blood vessel development. Here, we explored the nature of perlecan function during developmental angiogenesis...
  3. Zoeller J, McQuillan A, Whitelock J, Ho S, Iozzo R. A central function for perlecan in skeletal muscle and cardiovascular development. J Cell Biol. 2008;181:381-94 pubmed publisher
    b>Perlecan's developmental functions are difficult to dissect in placental animals because perlecan disruption is embryonic lethal...