Gene Symbol: hsf2
Description: heat shock transcription factor 2
Alias: zfHSF2, heat shock factor protein 2, heat shock factor 2, zK150H13.1.1 (heat shock factor 2)
Species: zebrafish

Top Publications

  1. Evans T, Belak Z, Ovsenek N, Krone P. Heat shock factor 1 is required for constitutive Hsp70 expression and normal lens development in embryonic zebrafish. Comp Biochem Physiol A Mol Integr Physiol. 2007;146:131-40 pubmed
    ..All three mammalian HSFs (HSF1, HSF2, HSF4) have also been shown to be required for normal mammalian development...
  2. Mathavan S, Lee S, Mak A, Miller L, Murthy K, Govindarajan K, et al. Transcriptome analysis of zebrafish embryogenesis using microarrays. PLoS Genet. 2005;1:260-76 pubmed
    ..The expression data generated from this study are accessible to all interested scientists from our institute resource database (http://giscompute.gis.a-star.edu.sg/~govind/zebrafish/data_download.html). ..
  3. Craig P, Hogstrand C, Wood C, McClelland G. Gene expression endpoints following chronic waterborne copper exposure in a genomic model organism, the zebrafish, Danio rerio. Physiol Genomics. 2009;40:23-33 pubmed publisher
    ..5% contained only a consensus MRE. We conclude that the indirect effects of Cu exposure regulate gene expression to a much greater degree than the direct effects. ..
  4. Swan C, Evans T, Sylvain N, Krone P. Zebrafish HSF4: a novel protein that shares features of both HSF1 and HSF4 of mammals. Cell Stress Chaperones. 2012;17:623-37 pubmed publisher
    ..This, together with the lack of an observable phenotype following morpholino-based antisense knockdown of hsf4, suggests that zHSF4 is unlikely to play a role in regulating early embryonic lens development. ..
  5. Kim S, Chang Z, Park J. Identification, tissue distribution and characterization of two heat shock factors (HSFs) in goldfish (Carassius auratus). Fish Shellfish Immunol. 2015;43:375-86 pubmed publisher
    ..paper reports the cDNA cloning of two goldfish (Carassius auratus) HSF gene families, HSF1 and three isoforms of HSF2. Both HSF1 and HSF2s showed high homology to the known HSFs from other organisms, particularly the zebrafish...
  6. Yeh F, Hsu L, Lin B, Chen C, Li I, Tsai S, et al. Cloning of zebrafish (Danio rerio) heat shock factor 2 (HSF2) and similar patterns of HSF2 and HSF1 mRNA expression in brain tissues. Biochimie. 2006;88:1983-8 pubmed
    ..Here we report the cloning of zebrafish (Danio rerio) HSF2 (zHSF2) cDNA (GenBank accession number AF412833 ) that has an open reading frame of 1470 nucleotides, encoding a ..
  7. Zheng J, Guo S, Yuan S, Xia H, Zhu Q, Lv Z. Preheating mitigates cadmium toxicity in zebrafish livers: Evidence from promoter demethylation, gene transcription to biochemical levels. Aquat Toxicol. 2017;190:104-111 pubmed publisher
    ..dismutase (Cu/Zn-SOD), and up-regulated mRNA levels of heat shock protein 70 (HSP70) and heat shock factor 2 (HSF2)...
  8. Zhu Q, Guo S, Yuan S, Lv Z, Zheng J, Xia H. Heat indicators of oxidative stress, inflammation and metal transport show dependence of cadmium pollution history in the liver of female zebrafish. Aquat Toxicol. 2017;191:1-9 pubmed publisher
    ..and iNOS; LPO; MT protein), 8 molecular indicators of oxidative stress (mRNA levels of Nrf2, Cu/Zn-SOD, CAT, HSF1, HSF2, HSP70, MTF-1 and MT), 5 molecular indicators of inflammation (mRNA levels of IL-6, IL-1?, TNF-?, iNOS and NF-?B), ..