Genomes and Genes
Gene Symbol: hbegfa
Description: heparin-binding EGF-like growth factor a
Alias: zgc:175091, heparin-binding EGF-like growth factor
- Kenyon A, Gavriouchkina D, Zorman J, Napolitani G, Cerundolo V, Sauka Spengler T. Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum. Sci Rep. 2017;7:6505 pubmed publisher..Further perturbation of the IEGs exposes egr3 as a key transcriptional regulator controlling il1Î² transcription. ..
- Lenkowski J, Qin Z, Sifuentes C, Thummel R, Soto C, Moens C, et al. Retinal regeneration in adult zebrafish requires regulation of TGF? signaling. Glia. 2013;61:1687-97 pubmed publisher..Tgif1 expression and regulation of TGF? signaling are implicated in the function of several types of stem cells, but this is the first demonstration that this regulatory network is necessary for regeneration of neurons. ..
- Xie L, Tang Q, Yang L, Chen L. Insulin-like growth factor I promotes oocyte maturation through increasing the expression and phosphorylation of epidermal growth factor receptor in the zebrafish ovary. Mol Cell Endocrinol. 2016;419:198-207 pubmed publisher..This study sheds light on the cross-talk between two important growth factors in the zebrafish ovary and the mechanism underlying the IGF-I induction on oocyte maturation. ..
- Schall K, Holoyda K, Grant C, Levin D, Torres E, Maxwell A, et al. Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration. Am J Physiol Gastrointest Liver Physiol. 2015;309:G135-45 pubmed publisher..We describe a technically feasible model of human SBS in the zebrafish, a faster and less expensive tool to investigate intestinal stem cell plasticity as well as the mechanisms that drive intestinal adaptation. ..