has1

Summary

Gene Symbol: has1
Description: hyaluronan synthase 1
Alias: hyaluronan synthase 1
Species: zebrafish

Top Publications

  1. Bakkers J, Kramer C, Pothof J, Quaedvlieg N, Spaink H, Hammerschmidt M. Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation. Development. 2004;131:525-37 pubmed
    ..In addition, they suggest that the same HA pathways are active to auto-stimulate cell migration during tumor invasion and vertebrate embryogenesis. ..
  2. Missinato M, Tobita K, Romano N, Carroll J, Tsang M. Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration. Cardiovasc Res. 2015;107:487-98 pubmed publisher
    ..HA and Hmmr are required for activated epicardial cell EMT and migration involving the FAK/Src pathway for proper heart regeneration. ..
  3. Govindan J, Tun K, Iovine M. Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration. PLoS ONE. 2016;11:e0148202 pubmed publisher
    ..Interactions between the ECM and signaling molecules are complex and our study demonstrates the requirement for components of the Hapln1a-ECM for Sema3d signal transduction. ..
  4. Han Y, Qian J, Zhang J, Hu C, Wang C. Structure-toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis. Toxicol Appl Pharmacol. 2017;327:39-51 pubmed publisher
    ..This study may provide bioinformatics and spectral information that may be used in further investigations on the relationship between structure and toxicity of drugs and impurities. ..