Gene Symbol: hapln1a
Description: hyaluronan and proteoglycan link protein 1a
Alias: crtl1, hapln1, wu:fc26f11, wu:fc37g04, wu:fc50e12, wu:fc55h01, hyaluronan and proteoglycan link protein 1, fc26f11, fc37g04, fc50e12, fc55h01, hyaluronan proteoglycan link protein 1
Species: zebrafish
Products:     hapln1a

Top Publications

  1. Kang J, Kawakami Y, Bekku Y, Ninomiya Y, Izpisua Belmonte J, Oohashi T. Molecular cloning and developmental expression of a hyaluronan and proteoglycan link protein gene, crtl1/hapln1, in zebrafish. Zoolog Sci. 2008;25:912-8 pubmed publisher
    ..the process of chondrogenesis and bone formation in zebrafish, we cloned the zebrafish cDNA for hyaluronan and proteoglycan link protein 1 (crtl1/hapln1) and examined the expression of the gene during embryogenesis using in-situ ..
  2. Govindan J, Iovine M. Dynamic remodeling of the extra cellular matrix during zebrafish fin regeneration. Gene Expr Patterns. 2015;19:21-9 pubmed publisher
    ..Additionally, we observed that the link protein Hapln1a dependent ECM, consisting of Hapln1a, hyaluronan and proteoglycan aggrecan, is upregulated during fin ..
  3. Govindan J, Iovine M. Hapln1a is required for connexin43-dependent growth and patterning in the regenerating fin skeleton. PLoS ONE. 2014;9:e88574 pubmed publisher
    ..In this study, we show that Hapln1a (Hyaluronan and Proteoglycan Link Protein 1a) functions downstream of cx43...
  4. Banerji R, Eble D, Iovine M, Skibbens R. Esco2 regulates cx43 expression during skeletal regeneration in the zebrafish fin. Dev Dyn. 2016;245:7-21 pubmed publisher
    ..These results conceptually link ODDD to cohesinopathies and provide evidence that ESCO2 may play a transcriptional role critical for human development. ..
  5. Govindan J, Tun K, Iovine M. Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration. PLoS ONE. 2016;11:e0148202 pubmed publisher
    ..studies have shown that the extra cellular matrix (ECM) protein Hyaluronan and Proteoglycan Link Protein1a (Hapln1a) is molecularly and functionally downstream of Cx43, and that hapln1a knockdown leads to reduction of the ..