h2afva

Summary

Gene Symbol: h2afva
Description: H2A histone family, member Va
Alias: H2A.F/Z, h2afv, h2afz, histone H2A.V, H2A histone family, member V, H2A histone family, member Z
Species: zebrafish

Top Publications

  1. doi Oocyte-specific H2A variant H2af1o is required for cell synchrony before midblastula transition in early zebrafish embryos
    Hua Mei Yue
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Graduate University of the Chinese Academy of Sciences, Wuhan, China
    Biol Reprod 89:82. 2013
  2. pmc Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization
    Gina L O'Grady
    Institute for Neuroscience and Muscle Research, Kid s Research Institute, Children s Hospital at Westmead, Sydney, NSW 2145, Australia Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW 2006, Australia Paediatric Neurology Service, Starship Children s Health, Auckland 1023, New Zealand
    Am J Hum Genet 99:1086-1105. 2016
  3. pmc Embryonic origin and lineage hierarchies of the neural progenitor subtypes building the zebrafish adult midbrain
    Sonya Galant
    Paris Saclay Institute for Neuroscience, CNRS UMR9197 Université Paris Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Bldg 5, F 91198 Gif sur Yvette, France
    Dev Biol 420:120-135. 2016
  4. pmc Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium
    Matthew J Foglia
    Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA
    Development 143:1688-96. 2016
  5. doi Glypican4 promotes cardiac specification and differentiation by attenuating canonical Wnt and Bmp signaling
    Ina Strate
    Department of Cardiac Development and Genetics, Hubrecht Institute and University Medical Center Utrecht, Utrecht 3584 CT, The Netherlands
    Development 142:1767-76. 2015
  6. pmc Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning
    Andrey Fadeev
    Max Planck Institute for Developmental Biology, Tubingen, Germany
    elife 4:. 2015
  7. pmc Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish
    Ching Hung Chen
    Department of Bioscience Technology, Chung Yuan Christian University, Chung Li, Taiwan
    Oncotarget 5:6300-11. 2014
  8. pmc Mosaic analysis and tumor induction in zebrafish by microsatellite instability-mediated stochastic gene expression
    Wouter Koole
    Department of Toxicogenetics, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands
    Dis Model Mech 7:929-36. 2014
  9. pmc Low temperature mitigates cardia bifida in zebrafish embryos
    Che Yi Lin
    Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan
    PLoS ONE 8:e69788. 2013
  10. pmc Cone photoreceptor types in zebrafish are generated by symmetric terminal divisions of dedicated precursors
    Sachihiro C Suzuki
    Department of Biological Structure, University of Washington, Seattle, WA 98195 7420
    Proc Natl Acad Sci U S A 110:15109-14. 2013

Scientific Experts

  • Sairatul D Ishak
  • Tamar E Sztal
  • Matthew J Foglia
  • Sonya Galant
  • Gina L O'Grady
  • Andrey Fadeev
  • Ina Strate
  • Wouter Koole
  • Ching Hung Chen
  • Chung Der Hsiao
  • Jennifer A Schumacher
  • Hua Mei Yue
  • Sachihiro C Suzuki
  • Che Yi Lin
  • Li En Jao
  • Bruce Appel
  • Kazuhide Asakawa
  • Carrie McMahon
  • Randolph K Roberts
  • Kristen M Kwan
  • Ryan Thummel
  • Ying Hu
  • Avnika A Ruparelia
  • Haluk Topaloglu
  • Beryl B Cummings
  • Biljana Ilkovski
  • Sandra T Cooper
  • Monkol Lek
  • Jean Francois Deleuze
  • Thierry Maisonobe
  • Leigh B Waddell
  • Vanessa Schartner
  • Marion Coolen
  • Nigel F Clarke
  • Myriam Sanjuan-Vazquez
  • Stephen W Reddel
  • Didem Ardicli
  • Kenneth D Poss
  • Tanya Stojkovic
  • Beril Talim
  • CARSTEN G BONNEMANN
  • Jahannaz Dastgir
  • Anne Boland
  • Jingli Cao
  • Viola Oorschot Ing
  • Sylvie Friant
  • Giacomo Furlan
  • Daniel G MacArthur
  • Himanshu Joshi
  • Lara Dirian
  • Anthony J Peduto
  • Heather A Best
  • Juliette Nectoux
  • ROGER BRYAN SUTTON
  • Robert J Bryson-Richardson
  • Kristen J Nowak
  • Sandra Donkervoort
  • Jocelyn Laporte
  • Kathryn N North
  • Laure Bally-Cuif
  • Norma Beatriz Romero
  • Osorio Abath Neto
  • Georg Ramm
  • Caitlin Williams
  • Valerie A Tornini
  • Taru Tukiainen
  • Isabelle Foucher
  • Nigel G Laing
  • Susan Brammah
  • Jana Krauss
  • Hans Georg Frohnhöfer
  • Christiane Nüsslein-Volhard
  • Jeroen Bakkers
  • Uwe Irion
  • Federico Tessadori
  • Yu Kang Lo
  • Chieh Wen Cheng
  • Chun Ju Lin
  • Chueh Chuan Yen
  • Alan Yueh Luen Lee
  • Marcel Tijsterman
  • Dar Shong Lin
  • Yang Wang
  • Joshua Bloomekatz
  • Masaki Takechi
  • Philip R Williams
  • Shoji Kawamura
  • Sheng Ping L Hwang
  • Adam Bleckert
  • Deborah Yelon

Detail Information

Publications21

  1. doi Oocyte-specific H2A variant H2af1o is required for cell synchrony before midblastula transition in early zebrafish embryos
    Hua Mei Yue
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Graduate University of the Chinese Academy of Sciences, Wuhan, China
    Biol Reprod 89:82. 2013
    ..Therefore, our current findings provided the first case to understand the biological function of maternal oocyte-specific histone variants in vertebrates. ..
  2. pmc Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization
    Gina L O'Grady
    Institute for Neuroscience and Muscle Research, Kid s Research Institute, Children s Hospital at Westmead, Sydney, NSW 2145, Australia Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW 2006, Australia Paediatric Neurology Service, Starship Children s Health, Auckland 1023, New Zealand
    Am J Hum Genet 99:1086-1105. 2016
    ..We characterize variants in the oxidoreductase PYROXD1 as a cause of early-onset myopathy with distinctive histopathology and introduce altered redox regulation as a primary cause of congenital muscle disease...
  3. pmc Embryonic origin and lineage hierarchies of the neural progenitor subtypes building the zebrafish adult midbrain
    Sonya Galant
    Paris Saclay Institute for Neuroscience, CNRS UMR9197 Université Paris Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Bldg 5, F 91198 Gif sur Yvette, France
    Dev Biol 420:120-135. 2016
    ..Together, our results highlight the shared recruitment of an identical neurogenic strategy by two remote brain territories, where long-lasting NE pools serve both as a growth zone and as the life-long source of young neurogenic RG cells...
  4. pmc Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium
    Matthew J Foglia
    Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA
    Development 143:1688-96. 2016
    ..Our findings reveal proliferation dynamics and fate decisions of cardiomyocytes that produce the distinct architecture of the atrium. ..
  5. doi Glypican4 promotes cardiac specification and differentiation by attenuating canonical Wnt and Bmp signaling
    Ina Strate
    Department of Cardiac Development and Genetics, Hubrecht Institute and University Medical Center Utrecht, Utrecht 3584 CT, The Netherlands
    Development 142:1767-76. 2015
    ..This provides a possible explanation for how congenital heart defects arise in glypican-deficient patients. ..
  6. pmc Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning
    Andrey Fadeev
    Max Planck Institute for Developmental Biology, Tubingen, Germany
    elife 4:. 2015
    ..Tjp1a is a novel regulator of cell shape changes during colour pattern formation and the first cytoplasmic protein implicated in this process. ..
  7. pmc Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish
    Ching Hung Chen
    Department of Bioscience Technology, Chung Yuan Christian University, Chung Li, Taiwan
    Oncotarget 5:6300-11. 2014
    ..Our findings and other characteristics of zebrafish, including optical clarity and small molecule treatment, provide the future utility of this model for easy and non-invasive detection and for identification of new anti-cancer drug. ..
  8. pmc Mosaic analysis and tumor induction in zebrafish by microsatellite instability-mediated stochastic gene expression
    Wouter Koole
    Department of Toxicogenetics, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands
    Dis Model Mech 7:929-36. 2014
    ..Our data demonstrate that inducing somatic mosaicism through microsatellite instability can be a valuable approach for mosaic analysis and tumor induction in Danio rerio. ..
  9. pmc Low temperature mitigates cardia bifida in zebrafish embryos
    Che Yi Lin
    Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan
    PLoS ONE 8:e69788. 2013
    ..Our study reveals that temperature coordinates the development of the heart tube and somitogenesis, and that extracellular matrix genes (fibronectin 1, tenascin-c and tenascin-w) are involved...
  10. pmc Cone photoreceptor types in zebrafish are generated by symmetric terminal divisions of dedicated precursors
    Sachihiro C Suzuki
    Department of Biological Structure, University of Washington, Seattle, WA 98195 7420
    Proc Natl Acad Sci U S A 110:15109-14. 2013
    ..Ectopic expression of trβ2 after cone differentiation produces cones with mixed opsins. Temporal differences in the onset of trβ2 expression could explain why some species have mixed, and others have pure, cone types. ..
  11. pmc tal1 Regulates the formation of intercellular junctions and the maintenance of identity in the endocardium
    Jennifer A Schumacher
    Developmental Genetics Program and Department of Cell Biology, Kimmel Center for Biology and Medicine, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
    Dev Biol 383:214-26. 2013
    ..We therefore propose a model in which Tal1 has distinct roles in regulating the formation of endocardial intercellular junctions and maintaining endocardial identity. ..
  12. doi Epistatic dissection of laminin-receptor interactions in dystrophic zebrafish muscle
    Tamar E Sztal
    Australian Regenerative Medicine Institute, Monash University, Clayton, VIC 3800, Australia
    Hum Mol Genet 21:4718-31. 2012
    ..Collectively these findings provide a better understanding of the cellular pathology of MDC1A and help in designing effective therapies...
  13. pmc A zebrafish model of lethal congenital contracture syndrome 1 reveals Gle1 function in spinal neural precursor survival and motor axon arborization
    Li En Jao
    Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, 465 21st Avenue South, Nashville, TN 37232 8240, USA
    Development 139:1316-26. 2012
    ..We propose that defective GLE1 function in human LCCS1 results in both neurogenic and non-neurogenic defects linked to the apoptosis of proliferative organ precursors...
  14. ncbi Two different transgenes to study gene silencing and re-expression during zebrafish caudal fin and retinal regeneration
    Ryan Thummel
    Center for Zebrafish Research and Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA
    ScientificWorldJournal 6:65-81. 2006
    ..Thus, we concluded that Tg(ef1-alpha:EGFP)nt line visually marks nonterminally differentiated cells in multiple adult regeneration environments and may prove to be a useful marker in tissue regeneration studies in zebrafish...
  15. doi A transgenic zebrafish for monitoring in vivo microtubule structures
    Kazuhide Asakawa
    Division of Molecular and Developmental Biology, National Institute of Genetics, Department of Genetics, Graduate University for Advanced Studies SOKENDAI, Mishima, Shizuoka, Japan
    Dev Dyn 239:2695-9. 2010
    ..Therefore, the transgenic UAS reporter line should be useful for directly monitoring MTs in the intact brain...
  16. pmc Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish
    Carrie McMahon
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Dev Biol 332:287-98. 2009
    ..Overall, we propose zebrafish lmx1b.1 and lmx1b.2 promote the survival of periocular mesenchymal cells that influence multiple signaling events required for proper ocular development...
  17. pmc Apical polarity protein PrkCi is necessary for maintenance of spinal cord precursors in zebrafish
    Randolph K Roberts
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA
    Dev Dyn 238:1638-48. 2009
    ..We conclude that PrkCi function and planar divisions are necessary for asymmetric, self-renewing division of spinal cord precursors...
  18. pmc Upregulated mRNA expression of desaturase and elongase, two enzymes involved in highly unsaturated fatty acids biosynthesis pathways during follicle maturation in zebrafish
    Sairatul D Ishak
    School of Biological Sciences, Universiti Sains Malaysia, Penang
    Reprod Biol Endocrinol 6:56. 2008
    ..Concurrently, the fatty acid profile of each follicle stage was also analyzed...
  19. ncbi The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
    Kristen M Kwan
    Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah, USA
    Dev Dyn 236:3088-99. 2007
    ..The Tol2kit greatly facilitates zebrafish transgenesis, simplifies the sharing of clones, and enables large-scale projects testing the functions of libraries of regulatory or coding sequences...