gngt1

Summary

Gene Symbol: gngt1
Description: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
Alias: gng1, wu:fk53d06, zgc:73318, guanine nucleotide-binding protein G(T) subunit gamma-T1, guanine nucleotide binding protein (G protein), gamma 1 subunit
Species: zebrafish

Top Publications

  1. Chen H, Leung T, Giger K, Stauffer A, Humbert J, Sinha S, et al. Expression of the G protein gammaT1 subunit during zebrafish development. Gene Expr Patterns. 2007;7:574-83 pubmed
    Here, we report the identification and expression analysis of the zebrafish G protein gammaT1 subunit gene (gngT1) during development...
  2. Mulligan T, Blaser H, Raz E, Farber S. Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish. Cell Signal. 2010;22:221-33 pubmed publisher
  3. Mulligan T, Farber S. Central and C-terminal domains of heterotrimeric G protein gamma subunits differentially influence the signaling necessary for primordial germ cell migration. Cell Signal. 2011;23:1617-24 pubmed publisher
    ..Residues found in the carboxy-terminal segment of G? transducin (gngt1) were found to be responsible for the ability of this subunit to disrupt PGC migration...
  4. Martins R, Vieira F, Power D. Calcitonin receptor family evolution and fishing for function using in silico promoter analysis. Gen Comp Endocrinol. 2014;209:61-73 pubmed publisher
  5. Lagman D, Callado Pérez A, Franzén I, Larhammar D, Abalo X. Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation. PLoS ONE. 2015;10:e0121330 pubmed publisher
    ..Early vertebrate tetraploidisations resulted in separate transducin heterotrimers: gnat1/gnb1/gngt1 for rods, and gnat2/gnb3/gngt2 for cones...
  6. Villeneuve L, Wang R, Bencic D, Biales A, Martinovic D, Lazorchak J, et al. Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation. Environ Toxicol Chem. 2009;28:1767-82 pubmed publisher
    ..These hypotheses and others derived from the microarray results provide a foundation for future studies aimed at understanding responses of the HPG axis to EACs and other chemical stressors. ..
  7. Khuansuwan S, Gamse J. Identification of differentially expressed genes during development of the zebrafish pineal complex using RNA sequencing. Dev Biol. 2014;395:144-53 pubmed publisher
    ..This protocol brings modern transcriptome analysis to the study of small cell populations in zebrafish. ..
  8. Feng D, Chen Z, Yang K, Miao S, Xu B, Kang Y, et al. The cytoplasmic tail of rhodopsin triggers rapid rod degeneration in kinesin-2 mutants. J Biol Chem. 2017;292:17375-17386 pubmed publisher
    ..Our results demonstrate a previously unknown function of the rhodopsin cytoplasmic domain during opsin-triggered photoreceptor degeneration and may open up new avenues for managing this disease. ..