Gene Symbol: gnb5b
Description: guanine nucleotide binding protein (G protein), beta 5b
Alias: gnb5, zgc:73196, guanine nucleotide-binding protein subunit beta-5b, guanine nucleotide binding protein (G protein), beta 5, guanine nucleotide-binding protein subunit beta-5
Species: zebrafish

Top Publications

  1. Kratz E, Eimon P, Mukhyala K, Stern H, Zha J, Strasser A, et al. Functional characterization of the Bcl-2 gene family in the zebrafish. Cell Death Differ. 2006;13:1631-40 pubmed
    ..These data indicate substantial functional similarity between zebrafish and mammalian Bcl-2 family members, and establish the zebrafish as a relevant model for studying the intrinsic apoptosis pathway. ..
  2. Mulligan T, Blaser H, Raz E, Farber S. Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish. Cell Signal. 2010;22:221-33 pubmed publisher
  3. Xu H, Kardash E, Chen S, Raz E, Lin F. G?? signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity. Development. 2012;139:57-62 pubmed publisher
    ..Our results indicate that during PGC migration in vivo, G?? signaling regulates Rac activity to control cell polarity, which is required for the responsiveness to chemokine signaling. ..
  4. Xu T, Zhao J, Xu Z, Pan R, Yin D. The developmental effects of pentachlorophenol on zebrafish embryos during segmentation: A systematic view. Sci Rep. 2016;6:25929 pubmed publisher
    ..Our study attempted to describe the developmental toxicity of environmental pollutants from a systematic view. Meanwhile, some features of gene expression profiling could serve as markers of human health or ecological risk. ..
  5. Lodder E, De Nittis P, Koopman C, Wiszniewski W, Moura de Souza C, Lahrouchi N, et al. GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability. Am J Hum Genet. 2016;99:704-710 pubmed publisher
    b>GNB5 encodes the G protein ? subunit 5 and is involved in inhibitory G protein signaling...