Gene Symbol: gnb5a
Description: guanine nucleotide binding protein (G protein), beta 5a
Alias: zgc:158678, guanine nucleotide-binding protein subunit beta-5a
Species: zebrafish

Top Publications

  1. Mulligan T, Blaser H, Raz E, Farber S. Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish. Cell Signal. 2010;22:221-33 pubmed publisher
  2. Xu H, Kardash E, Chen S, Raz E, Lin F. G?? signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity. Development. 2012;139:57-62 pubmed publisher
    ..Our results indicate that during PGC migration in vivo, G?? signaling regulates Rac activity to control cell polarity, which is required for the responsiveness to chemokine signaling. ..
  3. Lodder E, De Nittis P, Koopman C, Wiszniewski W, Moura de Souza C, Lahrouchi N, et al. GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability. Am J Hum Genet. 2016;99:704-710 pubmed publisher