Gene Symbol: galn
Description: galanin/GMAP prepropeptide
Alias: gal, ppg, galanin peptides
Species: zebrafish

Top Publications

  1. Woods I, Schoppik D, Shi V, Zimmerman S, Coleman H, Greenwood J, et al. Neuropeptidergic signaling partitions arousal behaviors in zebrafish. J Neurosci. 2014;34:3142-60 pubmed publisher
  2. Chen S, Reichert S, Singh C, Oikonomou G, Rihel J, Prober D. Light-Dependent Regulation of Sleep and Wake States by Prokineticin 2 in Zebrafish. Neuron. 2017;95:153-168.e6 pubmed publisher
    ..In light, Prok2 overexpression increases sleep and induces expression of galanin (galn), a hypothalamic sleep-inducing peptide...
  3. Pavlidis M, Sundvik M, Chen Y, Panula P. Adaptive changes in zebrafish brain in dominant-subordinate behavioral context. Behav Brain Res. 2011;225:529-37 pubmed publisher
    ..COMT), in the biosynthesis of histamine (histidine decarboxylase, HDC) and in the general stress response (galanin, GAL; hypocretin/orexin, Hcrt) was examined...
  4. Podlasz P, Sallinen V, Chen Y, Kudo H, Fedorowska N, Panula P. Galanin gene expression and effects of its knock-down on the development of the nervous system in larval zebrafish. J Comp Neurol. 2012;520:3846-62 pubmed publisher
    ..The results suggest that galanin does not regulate the development of these key markers of specific neurons, although galanin-expressing fibers were in a close spatial proximity to several neurons of these neuronal populations. ..
  5. Sundvik M, Chen Y, Panula P. Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio. J Neurosci. 2013;33:1589-97 pubmed publisher
    ..The new histaminergic neurons in aging zebrafish brain may arise as a result of phenotypic plasticity or represent newly differentiated stem cells...
  6. Howe K, Clark M, Torroja C, Torrance J, Berthelot C, Muffato M, et al. The zebrafish reference genome sequence and its relationship to the human genome. Nature. 2013;496:498-503 pubmed publisher
  7. Kim D, Yun S, Son G, Hwang J, Park C, Kim J, et al. Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III. Endocrinology. 2014;155:1864-73 pubmed publisher
    ..ancestral chromosomes revealed that SPXs reside in the near vicinity of the kisspeptin (KISS) and galanin (GAL) family genes on the chromosomes...
  8. Sterling M, Karatayev O, Chang G, Algava D, Leibowitz S. Model of voluntary ethanol intake in zebrafish: effect on behavior and hypothalamic orexigenic peptides. Behav Brain Res. 2015;278:29-39 pubmed publisher
    ..of this ethanol intake on different behaviors and the expression of hypothalamic orexigenic peptides, galanin (GAL) and orexin (OX), which are known in rodents to stimulate consumption of ethanol and alter behaviors associated ..
  9. Sterling M, Chang G, Karatayev O, Chang S, Leibowitz S. Effects of embryonic ethanol exposure at low doses on neuronal development, voluntary ethanol consumption and related behaviors in larval and adult zebrafish: Role of hypothalamic orexigenic peptides. Behav Brain Res. 2016;304:125-38 pubmed publisher
    ..increased hypothalamic neurogenesis and the proliferation and expression of the orexigenic peptides, galanin (GAL) and orexin (OX), in the anterior hypothalamus...

More Information


  1. Förster D, Arnold Ammer I, Laurell E, Barker A, Fernandes A, Finger Baier K, et al. Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools. Sci Rep. 2017;7:5230 pubmed publisher
    ..Taken together, our study offers new tools for functional studies of specific neural circuits in zebrafish. ..
  2. Lovett Barron M, Andalman A, Allen W, Vesuna S, Kauvar I, Burns V, et al. Ancestral Circuits for the Coordinated Modulation of Brain State. Cell. 2017;171:1411-1423.e17 pubmed publisher
    ..These experiments establish a method for unbiased discovery of cellular elements underlying behavior and reveal an evolutionarily conserved set of diverse neuromodulatory systems that collectively govern internal state. ..