Gene Symbol: gabbr1a
Description: gamma-aminobutyric acid (GABA) B receptor, 1a
Alias: gabbr1, gamma-aminobutyric acid type B receptor subunit 1, gaba1, gamma-aminobutyric acid (GABA) B receptor, 1
Bjarnadóttir T, Fredriksson R, Schioth H. The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors. Gene. 2005;362:70-84 pubmed
..This report provides a comprehensive overview of the expansion/deletions of the groups within the Glutamate receptor family. ..
Delgado L, Schmachtenberg O. Immunohistochemical localization of GABA, GAD65, and the receptor subunits GABAAalpha1 and GABAB1 in the zebrafish cerebellum. Cerebellum. 2008;7:444-50 pubmed publisher
..These results are compared to the expression of the GABAergic system in the mammalian cerebellum. ..
Brockerhoff S, Rieke F, Matthews H, Taylor M, Kennedy B, Ankoudinova I, et al
. Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and suppression of current in cones from the zebrafish mutant nof. J Neurosci. 2003;23:470-80 pubmed
..Thus, in addition to stimulating transducin, light also independently induces release of Ca2+ into the photoreceptor cytoplasm. ..
Pan Y, Chatterjee D, Gerlai R. Strain dependent gene expression and neurochemical levels in the brain of zebrafish: focus on a few alcohol related targets. Physiol Behav. 2012;107:773-80 pubmed publisher
..They now also allow formulation of working hypotheses about possible mechanisms underlying the differential effects of acute and chronic alcohol treatment on these two zebrafish strains. ..
Wong R, McLeod M, Godwin J. Limited sex-biased neural gene expression patterns across strains in Zebrafish (Danio rerio). BMC Genomics. 2014;15:905 pubmed publisher
..A possible mechanism is through regulating specific brain gene networks. ..
Wong R, Lamm M, Godwin J. Characterizing the neurotranscriptomic states in alternative stress coping styles. BMC Genomics. 2015;16:425 pubmed publisher
Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, et al
. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLoS Genet. 2017;13:e1006892 pubmed publisher
..These findings suggest that either activating ATP2C1 or restoring the Mn-induced trafficking of ATP2C1 can reduce Mn accumulation, providing a possible target for treating HMDPC. ..