foxp2

Summary

Gene Symbol: foxp2
Description: forkhead box P2
Alias: forkhead box protein P2
Species: zebrafish

Top Publications

  1. pmc Domain-specific regulation of foxP2 CNS expression by lef1
    Joshua L Bonkowsky
    Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    BMC Dev Biol 8:103. 2008
  2. ncbi Molecular cloning, characterization, and developmental expression of foxp1 in zebrafish
    Lu Cheng
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, 200433, People s Republic of China
    Dev Genes Evol 217:699-707. 2007
  3. pmc Hypoxia disruption of vertebrate CNS pathfinding through ephrinB2 Is rescued by magnesium
    Tamara J Stevenson
    Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
    PLoS Genet 8:e1002638. 2012
  4. ncbi Molecular cloning and developmental expression of foxP2 in zebrafish
    Joshua L Bonkowsky
    Department of Pediatric Neurology and Pediatrics, University of Utah Medical Center, Salt Lake City, Utah 84132, USA
    Dev Dyn 234:740-6. 2005
  5. ncbi Expression of FoxP2 during zebrafish development and in the adult brain
    Rina Shah
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Int J Dev Biol 50:435-8. 2006
  6. pmc Zebrafish foxP2 zinc finger nuclease mutant has normal axon pathfinding
    Lingyan Xing
    Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
    PLoS ONE 7:e43968. 2012
  7. pmc Discovery and assessment of conserved Pax6 target genes and enhancers
    Pedro Coutinho
    Medical Research Council MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
    Genome Res 21:1349-59. 2011

Scientific Experts

  • J L Bonkowsky
  • Pedro Coutinho
  • Tamara J Stevenson
  • Esther Fujimoto
  • Lingyan Xing
  • Lu Cheng
  • Rina Shah
  • Chi Bin Chien
  • Cory Kogelschatz
  • Kazuyuki Hoshijima
  • David J Grunwald
  • Cameron J Brimley
  • Tony Trinh
  • Jacob Sneddon
  • Tyler S Quist
  • Tatjana Piotrowski
  • Mark E Lush
  • Yonghao Gui
  • Xueyan Yang
  • Xiaofang Guo
  • Fan Liu
  • Daru Lu
  • Wenjuan Zhang
  • Mei Chong
  • Weiwei Fan
  • Milan Jamrich
  • Li Fang Chu
  • Rodney C Samaco
  • Olga Medina-Martinez

Detail Information

Publications7

  1. pmc Domain-specific regulation of foxP2 CNS expression by lef1
    Joshua L Bonkowsky
    Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    BMC Dev Biol 8:103. 2008
    b>FOXP2 is a forkhead transcription factor critical for normal development of language in humans, but little is known of its broader function and regulation during central nervous system (CNS) development...
  2. ncbi Molecular cloning, characterization, and developmental expression of foxp1 in zebrafish
    Lu Cheng
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, 200433, People s Republic of China
    Dev Genes Evol 217:699-707. 2007
    ..These results provide evidence that foxp1 is likely to function as a very important transcription factor in the development of the central nervous system and many other organs in zebrafish...
  3. pmc Hypoxia disruption of vertebrate CNS pathfinding through ephrinB2 Is rescued by magnesium
    Tamara J Stevenson
    Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
    PLoS Genet 8:e1002638. 2012
    ..These results demonstrate that evolutionarily conserved genetic pathways regulate connectivity changes in the CNS in response to hypoxia, and they support a potential neuroprotective role for magnesium...
  4. ncbi Molecular cloning and developmental expression of foxP2 in zebrafish
    Joshua L Bonkowsky
    Department of Pediatric Neurology and Pediatrics, University of Utah Medical Center, Salt Lake City, Utah 84132, USA
    Dev Dyn 234:740-6. 2005
    Forkhead domain transcription factors are a large gene family with multiple roles in development. FOXP2, a recently identified member of this family, has been shown to be critical for normal development of language in humans, but little ..
  5. ncbi Expression of FoxP2 during zebrafish development and in the adult brain
    Rina Shah
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Int J Dev Biol 50:435-8. 2006
    ..Mutations in the human FOXP2 gene cause abnormal speech development. Here we report the structure and expression pattern of zebrafish FoxP2...
  6. pmc Zebrafish foxP2 zinc finger nuclease mutant has normal axon pathfinding
    Lingyan Xing
    Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
    PLoS ONE 7:e43968. 2012
    b>foxP2, a forkhead-domain transcription factor, is critical for speech and language development in humans, but its role in the establishment of CNS connectivity is unclear...
  7. pmc Discovery and assessment of conserved Pax6 target genes and enhancers
    Pedro Coutinho
    Medical Research Council MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
    Genome Res 21:1349-59. 2011
    ..We have identified several novel direct targets, including some putative disease genes, among them Foxp2; these will allow further dissection of Pax6 function in development and disease.