Genomes and Genes
Gene Symbol: fli1b
Description: Fli-1 proto-oncogene, ETS transcription factor b
Alias: zgc:5777174, Fli-1 proto-oncogene, ETS transcription factor b, fli-1 proto-oncogene, ETS transcription factor b, fli-1 homolog, friend leukemia integration 1b
- Moore J, Sheppard Tindell S, Shestopalov I, Yamazoe S, Chen J, Lawson N. Post-transcriptional mechanisms contribute to Etv2 repression during vascular development. Dev Biol. 2013;384:128-40 pubmed publisher..Taken together, our results suggest that etv2 acts during early development to specify endothelial lineages and is then down-regulated, in part through post-transcriptional repression by microRNAs, to allow normal vascular development. ..
- Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, et al. Regulation of Î²1 integrin-Klf2-mediated angiogenesis by CCM proteins. Dev Cell. 2015;32:181-90 pubmed publisher..Our work reveals a Î²1 integrin-Klf2-Egfl7-signaling pathway that is tightly regulated by CCM proteins. This regulation prevents angiogenic overgrowth and ensures the quiescence of endothelial cells. ..
- Missinato M, Tobita K, Romano N, Carroll J, Tsang M. Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration. Cardiovasc Res. 2015;107:487-98 pubmed publisher..HA and Hmmr are required for activated epicardial cell EMT and migration involving the FAK/Src pathway for proper heart regeneration. ..
- Baltrunaite K, Craig M, Palencia Desai S, Chaturvedi P, Pandey R, Hegde R, et al. ETS transcription factors Etv2 and Fli1b are required for tumor angiogenesis. Angiogenesis. 2017;20:307-323 pubmed publisher..B16 melanoma cells resulted in a significant increase in expression of the ETS transcription factors etv2 and fli1b expression throughout the embryonic vasculature...