Gene Symbol: fgf19
Description: fibroblast growth factor 19
Alias: fibroblast growth factor 19
Nakayama Y, Miyake A, Nakagawa Y, Mido T, Yoshikawa M, Konishi M, et al
. Fgf19 is required for zebrafish lens and retina development. Dev Biol. 2008;313:752-66 pubmed
Fgf signaling plays crucial roles in morphogenesis. Fgf19 is required for zebrafish forebrain development. Here, we examined the roles of Fgf19 in the formation of the lens and retina in zebrafish...
Vinothkumar S, Rastegar S, Takamiya M, Ertzer R, Strahle U. Sequential and cooperative action of Fgfs and Shh in the zebrafish retina. Dev Biol. 2008;314:200-14 pubmed publisher
..We provide evidence that Fgf3 and -8 control initiation of expression, while Fgf19 is crucial for the propagation of transgene expression through the retina...
Yamauchi H, Miyakawa N, Miyake A, Itoh N. Fgf4 is required for left-right patterning of visceral organs in zebrafish. Dev Biol. 2009;332:177-85 pubmed publisher
..The present findings indicate that Fgf4 plays a unique role in the LR patterning of visceral organs in zebrafish. ..
Mangos S, Amaral A, Faul C, Juppner H, Reiser J, Wolf M. Expression of fgf23 and ?klotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio. Nephrol Dial Transplant. 2012;27:4314-22 pubmed publisher
..These data indicate conservation of the FGF23-?klotho system across species and suggest a likely role for ?klotho in the proximal and distal tubules. ..
Zhang C, Ojiaku P, Cole G. Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. Birth Defects Res A Clin Mol Teratol. 2013;97:8-27 pubmed publisher
..In zebrafish, forebrain GABAergic neuron development is dependent on Fgf19 and Shh signaling...
Katoh M, Katoh M. Evolutionary conservation of CCND1-ORAOV1-FGF19-FGF4 locus from zebrafish to human. Int J Mol Med. 2003;12:45-50 pubmed
The CCND1-ORAOV1-FGF19-FGF4-FGF3-FLJ10261-FADD-PPFIA1-EMS1 locus on human chromosome 11q13 is frequently amplified in esophageal cancer, breast cancer, and bladder tumors...
Miyake A, Nakayama Y, Konishi M, Itoh N. Fgf19 regulated by Hh signaling is required for zebrafish forebrain development. Dev Biol. 2005;288:259-75 pubmed
..Fgf8 is also required for the midbrain to form. Here, we identified zebrafish Fgf19 and examined its roles in brain development by knocking down Fgf19 function...
Tamimi Y, Skarie J, Footz T, Berry F, Link B, Walter M. FGF19 is a target for FOXC1 regulation in ciliary body-derived cells. Hum Mol Genet. 2006;15:3229-40 pubmed
..nickel agarose chromatin enrichment with human anterior segment cells, we previously identified the fibroblast growth factor 19 (FGF19) locus as a gene potentially regulated by FOXC1...