fancl

Summary

Gene Symbol: fancl
Description: Fanconi anemia, complementation group L
Alias: zgc:66144, zgc:76938, E3 ubiquitin-protein ligase FANCL
Species: zebrafish

Top Publications

  1. Titus T, Yan Y, Wilson C, Starks A, Frohnmayer J, Bremiller R, et al. The Fanconi anemia/BRCA gene network in zebrafish: embryonic expression and comparative genomics. Mutat Res. 2009;668:117-32 pubmed publisher
  2. Rodriguez Mari A, Canestro C, Bremiller R, Nguyen Johnson A, Asakawa K, Kawakami K, et al. Sex reversal in zebrafish fancl mutants is caused by Tp53-mediated germ cell apoptosis. PLoS Genet. 2010;6:e1001034 pubmed publisher
    ..We identified a mutation in the zebrafish fancl gene that causes homozygous mutants to develop as fertile males due to female-to-male sex reversal...
  3. Bagheri H, Badduke C, Qiao Y, Colnaghi R, Abramowicz I, Alcantara D, et al. Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis. JCI Insight. 2016;1:e85461 pubmed
    ..Our multifaceted analysis strongly implicates XPO1, REL, and BCL11A as candidate genes for 2p15p16.1 microdeletion syndrome. ..
  4. Hartung O, Forbes M, Marlow F. Zebrafish vasa is required for germ-cell differentiation and maintenance. Mol Reprod Dev. 2014;81:946-61 pubmed publisher
    ..Our studies provide insight into the function of zebrafish vasa during female meiosis, differentiation, and maintenance of germ-line stem cells. ..