fancd2

Summary

Gene Symbol: fancd2
Description: Fanconi anemia, complementation group D2
Alias: Fanconi anemia group D2 protein
Species: zebrafish

Top Publications

  1. Liu T, Howlett N, Deng M, Langenau D, Hsu K, Rhodes J, et al. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Dev Cell. 2003;5:903-14 pubmed
    ..We have identified the zebrafish homolog of human FANCD2, which encodes a nuclear effector protein that is monoubiquitinated in response to DNA damage, targeting it to ..
  2. Chen C, Kennedy R, Sidi S, Look A, D ANDREA A. CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Mol Cancer. 2009;8:24 pubmed publisher
    ..To confirm these findings in vivo, we demonstrated that whole zebrafish embryos, depleted for FANCD2 by a morpholino approach, were hypersensitive to Gö6976...
  3. Titus T, Yan Y, Wilson C, Starks A, Frohnmayer J, Bremiller R, et al. The Fanconi anemia/BRCA gene network in zebrafish: embryonic expression and comparative genomics. Mutat Res. 2009;668:117-32 pubmed publisher