Gene Symbol: fadd
Description: Fas (tnfrsf6)-associated via death domain
Alias: protein FADD, FAS-associated death domain protein
Species: zebrafish

Top Publications

  1. Zhao X, Zhao L, Tian T, Zhang Y, Tong J, Zheng X, et al. Interruption of cenph causes mitotic failure and embryonic death, and its haploinsufficiency suppresses cancer in zebrafish. J Biol Chem. 2010;285:27924-34 pubmed publisher
    ..Taken together, our findings uncover an essential role of cenph in mitosis and embryonic development and its association with tumor development. ..
  2. Viringipurampeer I, Ferreira T, DeMaria S, Yoon J, Shan X, Moosajee M, et al. Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development. Hum Mol Genet. 2012;21:2357-69 pubmed publisher
    ..analysis, we now establish that pax2 in combination with vax2 directly regulate the fas-associated death domain (fadd) gene...
  3. Zhou Z, Sun L. Edwardsiella tarda-Induced Inhibition of Apoptosis: A Strategy for Intracellular Survival. Front Cell Infect Microbiol. 2016;6:76 pubmed publisher
    ..tarda prevents apoptosis in teleost as a strategy for intracellular survival, and that some putative apoptotic genes of teleost function in the apoptosis pathway probably in a manner similar to that in mammalian systems. ..
  4. Serbanovic Canic J, De Luca A, Warboys C, Ferreira P, Luong L, Hsiao S, et al. Zebrafish Model for Functional Screening of Flow-Responsive Genes. Arterioscler Thromb Vasc Biol. 2017;37:130-143 pubmed publisher
  5. Gregory Evans C, Moosajee M, Hodges M, Mackay D, Game L, Vargesson N, et al. SNP genome scanning localizes oto-dental syndrome to chromosome 11q13 and microdeletions at this locus implicate FGF3 in dental and inner-ear disease and FADD in ocular coloboma. Hum Mol Genet. 2007;16:2482-93 pubmed
    ..In addition, the Fas-associated death domain (FADD) gene was also deleted in the one family segregating ocular coloboma...