Gene Symbol: ephb3a
Description: eph receptor B3a
Alias: ek3, ephb3, fc62d03, rtk3, wu:fc62d03, zek3, ephrin type-B receptor 3, eph-like kinase 3, eph-like receptor tyrosine kinase 3, epha3a, tyrosine-protein kinase receptor ZEK3
Species: zebrafish

Top Publications

  1. Zhang J, Jiang Z, Liu X, Meng A. Eph/ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016;143:2603-15 pubmed publisher
    ..Therefore, our data uncover an important role of Eph/ephrin signaling in maintaining DFC cluster boundary and KV boundary for normal left-right asymmetrical development. ..
  2. Bernhardt R. Cellular and molecular bases of axonal pathfinding during embryogenesis of the fish central nervous system. J Neurobiol. 1999;38:137-60 pubmed
    ..Experimental evidence for the functions of these molecules in the zebrafish nervous system is accumulating. In the future, this analysis is expected to profit greatly from genetic screens that have recently been initiated. ..
  3. French C, Erickson T, French D, Pilgrim D, Waskiewicz A. Gdf6a is required for the initiation of dorsal-ventral retinal patterning and lens development. Dev Biol. 2009;333:37-47 pubmed publisher
    ..Taken together, these data indicate that Gdf6a initiates dorsal retinal patterning independent of Bmp4, and regulates lens differentiation. ..
  4. Xu Q, Holder N, Patient R, Wilson S. Spatially regulated expression of three receptor tyrosine kinase genes during gastrulation in the zebrafish. Development. 1994;120:287-99 pubmed
    ..in precursor cells of the notochord in the tail bud but is downregulated in other regions of the axial hypoblast, rtk3 is expressed in anterior axial hypoblast including the 'pillow' at the anterior tip of the hypoblast and in ..
  5. Xu Q, Alldus G, Holder N, Wilkinson D. Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development. 1995;121:4005-16 pubmed
    ..These data suggest that Sek-1, perhaps with other Eph-related receptors, is required for interactions that regulate the segmental identity or movement of cells. ..
  6. Holly V, Widen S, Famulski J, Waskiewicz A. Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development. Dev Biol. 2014;388:192-204 pubmed publisher
    ..Overexpression of a low dose of sfrp5 mRNA causes an increase in dorsal retina marker gene expression. We propose a model in which Sfrp proteins function as facilitators of both BMP and Wnt signaling within the dorsal retina. ..
  7. Xiao Y, Jiang J, Hu W, Zhao Y, Hu J. Toxicity of triphenyltin on the development of retinal axons in zebrafish at low dose. Aquat Toxicol. 2017;189:9-15 pubmed publisher
    ..This study is the first to report that TPT can interfere with development of retinal axons in fish at low dose. ..