emp2

Summary

Gene Symbol: emp2
Description: epithelial membrane protein 2
Alias: EMP-2, zgc:100935, epithelial membrane protein 2
Species: zebrafish

Top Publications

  1. Ebarasi L, He L, Hultenby K, Takemoto M, Betsholtz C, Tryggvason K, et al. A reverse genetic screen in the zebrafish identifies crb2b as a regulator of the glomerular filtration barrier. Dev Biol. 2009;334:1-9 pubmed publisher
    ..This report is the first to show a role for crb function in podocyte differentiation. Furthermore, these results suggest a novel link between epithelial polarization and the maintenance of a functional filtration barrier. ..
  2. Gee H, Ashraf S, Wan X, Vega Warner V, Esteve Rudd J, Lovric S, et al. Mutations in EMP2 cause childhood-onset nephrotic syndrome. Am J Hum Genet. 2014;94:884-90 pubmed publisher
    ..We thereby detected biallelic mutations in EMP2 (epithelial membrane protein 2) in four individuals from three unrelated families affected by SRNS or SSNS...
  3. Wan X, Chen Z, Choi W, Gee H, Hildebrandt F, Zhou W. Loss of Epithelial Membrane Protein 2 Aggravates Podocyte Injury via Upregulation of Caveolin-1. J Am Soc Nephrol. 2016;27:1066-75 pubmed publisher
    ..We previously identified mutations in epithelial membrane protein 2 (EMP2) as a monogenic cause of this disease...