elp4

Summary

Gene Symbol: elp4
Description: elongator acetyltransferase complex subunit 4
Alias: wu:fi38c09, zgc:112389, elongator complex protein 4, elongation protein 4 homolog, fi38c09
Species: zebrafish

Top Publications

  1. Kikuta H, Laplante M, Navratilova P, Komisarczuk A, Engström P, Fredman D, et al. Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates. Genome Res. 2007;17:545-55 pubmed
    ..These findings explain the absence of evolutionary breakpoints from large vertebrate chromosomal segments and will aid in the recognition of position effect mutations within human GRBs. ..
  2. Feiner N, Meyer A, Kuraku S. Evolution of the vertebrate Pax4/6 class of genes with focus on its novel member, the Pax10 gene. Genome Biol Evol. 2014;6:1635-51 pubmed publisher
  3. Kleinjan D, Bancewicz R, Gautier P, Dahm R, Schonthaler H, Damante G, et al. Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence. PLoS Genet. 2008;4:e29 pubmed publisher
    ..control sequences, which in most vertebrates reside within the introns of a ubiquitously expressed neighbour gene, ELP4, whose pax6a-linked exons have been lost in zebrafish...
  4. Navratilova P, Fredman D, Hawkins T, Turner K, Lenhard B, Becker T. Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Dev Biol. 2009;327:526-40 pubmed publisher
    ..human HCNEs. HCNEs from the same area often drive overlapping patterns, suggesting that multiple regulatory inputs are required to achieve robust and precise complex expression patterns exhibited by developmental genes. ..
  5. Bhatia S, Monahan J, Ravi V, Gautier P, Murdoch E, Brenner S, et al. A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos. Dev Biol. 2014;387:214-28 pubmed publisher
    ..Remarkable overlap in expression patterns driven by sets of agCNEs indicates that PAX6 resides in a landscape of multiple tissue-specific regulatory archipelagos. ..