Gene Symbol: ela2l
Description: elastase 2 like
Alias: ctrc, elastaseB, fi40a05, wu:fi40a05, zgc:111871, zgc:63744, elastase 2 like, caldecrin, chymotrypsin C, elastase B
Wang H, Zhou Q, Kesinger J, Norris C, Valdez C. Heme regulates exocrine peptidase precursor genes in zebrafish. Exp Biol Med (Maywood). 2007;232:1170-80 pubmed
..genes, carboxypeptidase A, trypsin precursor, trypsin like, chymotrypsinogen B1, chymotrypsinogen 1-like, and elastase 2 like, are downregulated in yquem/urod (-/-), identified initially by microarray analysis of yquem/urod zebrafish ..
Mudumana S, Wan H, Singh M, Korzh V, Gong Z. Expression analyses of zebrafish transferrin, ifabp, and elastaseB mRNAs as differentiation markers for the three major endodermal organs: liver, intestine, and exocrine pancreas. Dev Dyn. 2004;230:165-73 pubmed
..work, three zebrafish cDNA clones encoding transferrin, intestinal fatty acid binding protein (IFABP), and elastaseB were cloned and their expression patterns in early zebrafish development were characterized as differentiation ..
Holtzinger A, Evans T. Gata4 regulates the formation of multiple organs. Development. 2005;132:4005-14 pubmed
..In addition, both Gata4 and Gata6 are essential and non-redundant for liver growth following initial budding. ..
Farooq M, Sulochana K, Pan X, To J, Sheng D, Gong Z, et al
. Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish. Dev Biol. 2008;317:336-53 pubmed publisher
..These results revealed a novel and specific role of hdac3 in liver development and the distinct functions between hdac1 and hdac3 in zebrafish embryonic development. ..
Zhang S, Xu M, Huang J, Tang L, Zhang Y, Wu J, et al
. Heme acts through the Bach1b/Nrf2a-MafK pathway to regulate exocrine peptidase precursor genes in porphyric zebrafish. Dis Model Mech. 2014;7:837-45 pubmed publisher
..These results provide novel insights into the regulation of exocrine function, as well as the pathogenesis of porphyria, and should be useful for designing new therapies for both types of disease. ..