Gene Symbol: EF 2
Description: eukaryotic translation elongation factor 2b
Alias: EEF2, eef2l, fe49h02, wu:fe49h02, zgc:63584, eukaryotic translation elongation factor 2b, EF-2, eukaryotic translation elongation factor 2, like
Sarath Babu N, Murthy C, Kakara S, Sharma R, Brahmendra Swamy C, Idris M. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish. Proteomics. 2016;16:1407-20 pubmed publisher
..This zebrafish based PD model can be used as a potential model system for screening prospective drug molecules for PD. ..
Hurem S, Martín L, Brede D, Skjerve E, Nourizadeh Lillabadi R, Lind O, et al
. Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression. PLoS ONE. 2017;12:e0179259 pubmed publisher
..The present findings show that continuous gamma irradiation (? 0.54 mGy/h) during early gastrula causes gene expression changes that are linked to developmental defects in zebrafish embryos. ..
Zhang S, Yao J, Song H, Wang L, Xue J. Cloning, expression and functional study of translation elongation factor 2 (EF-2) in zebrafish. Int J Dev Biol. 2006;50:399-403 pubmed
..Furthermore, their tails were incurvate and their lenses were much smaller than those of the normal embryos. However the EF-2 overexpression data showed that extra EF-2 protein had no obvious effect on zebrafish embryonic development. ..
Zhang S, Yao J, Song H, Wang L, Xue J. Cloning and expression of translation elongation factor 2 (EF-2) in zebrafish. DNA Seq. 2008;19:1-7 pubmed publisher
..Then the stained cells concentrate strongly in the eyes, brain and muscle tissue. From prim-25 stage the stained cells only appear strongly in the lens and the anterior portion of the cerebellum. ..
De Wit M, Keil D, van der Ven K, Vandamme S, Witters E, De Coen W. An integrated transcriptomic and proteomic approach characterizing estrogenic and metabolic effects of 17 alpha-ethinylestradiol in zebrafish (Danio rerio). Gen Comp Endocrinol. 2010;167:190-201 pubmed publisher
..Overall, this study demonstrated that a proteomics approach can lift the biological interpretation of microarrays to a higher level, and moreover, opens a window for identification of possible new biomarkers. ..