Gene Symbol: dermacan
Description: versican b
Alias: cspg2b, dcan, fb99b07, wu:fb99b07, versican b, chondroitin sulfate proteoglycan 2b, dermacan
Kang J, Oohashi T, Kawakami Y, Bekku Y, Izpisua Belmonte J, Ninomiya Y. Characterization of dermacan, a novel zebrafish lectican gene, expressed in dermal bones. Mech Dev. 2004;121:301-12 pubmed
We report here the isolation and characterization of a cDNA encoding zebrafish dermacan, a novel member of hyaluronan (HA)-binding proteoglycans, which was termed after its characteristic expression in the zebrafish dermal bones...
Postlethwait J. The zebrafish genome in context: ohnologs gone missing. J Exp Zool B Mol Dev Evol. 2007;308:563-77 pubmed
Kang J, Kawakami Y, Bekku Y, Ninomiya Y, Izpisua Belmonte J, Oohashi T. Molecular cloning and developmental expression of a hyaluronan and proteoglycan link protein gene, crtl1/hapln1, in zebrafish. Zoolog Sci. 2008;25:912-8 pubmed publisher
..During chondrocranial/skull formation, crtl1/hapln1 expression is highest at around 4 dpf and is colocalized with aggrecan in the cartilaginous arches and with dermacan in the dermal bones.
Wang X, Yu Q, Wu Q, Bu Y, Chang N, Yan S, et al
. Genetic interaction between pku300 and fbn2b controls endocardial cell proliferation and valve development in zebrafish. J Cell Sci. 2013;126:1381-91 pubmed publisher
..We conclude that pku300 and fbn2b represent the few genes capable of regulating endocardial cell proliferation and signaling in zebrafish cardiac valve development. ..
Lee H, Lo H, Lo D, Su M, Hu J, Wu C, et al
. Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos. PLoS ONE. 2015;10:e0144751 pubmed publisher
..Here, we proved that Amiodarone acts as an upstream regulator, stimulating similar to versican b (s-vcanb) overexpression at zebrafish embryonic heart and promoting cdh-5 overexpression by inhibiting snail1b ..