cx36.7

Summary

Gene Symbol: cx36.7
Description: connexin 36.7
Alias: cx35.8, ecx, ftk, zfcx41.04, connexin 36.7, connexin 35.8, zfconnexin 41.04
Species: zebrafish

Top Publications

  1. Miyagi H, Nag K, Sultana N, Munakata K, Hirose S, Nakamura N. Characterization of the zebrafish cx36.7 gene promoter: Its regulation of cardiac-specific expression and skeletal muscle-specific repression. Gene. 2016;577:265-74 pubmed publisher
    Zebrafish connexin 36.7 (cx36.7/ecx) has been identified as a key molecule in the early stages of heart development in this species. A defect in cx36.7 causes severe heart malformation due to the downregulation of nkx2...
  2. Sultana N, Nag K, Hoshijima K, Laird D, Kawakami A, Hirose S. Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression. Proc Natl Acad Sci U S A. 2008;105:4763-8 pubmed publisher
    ..We identified ftk to be a loss-of-function mutation in a connexin gene, cx36.7/early cardiac connexin (ecx), expressed during early heart development. We further showed by a rescue experiment that Nkx2...
  3. Li H, Chuang A, O BRIEN J. Photoreceptor coupling is controlled by connexin 35 phosphorylation in zebrafish retina. J Neurosci. 2009;29:15178-86 pubmed publisher
    ..Furthermore, the nighttime state is characterized by extensive coupling that results in a well connected cone network. ..
  4. Kurtenbach S, Prochnow N, Kurtenbach S, Klooster J, Zoidl C, Dermietzel R, et al. Pannexin1 channel proteins in the zebrafish retina have shared and unique properties. PLoS ONE. 2013;8:e77722 pubmed publisher
    ..The existence of two Panx1 proteins in zebrafish displaying distinct tissue distribution, protein modification and electrophysiological properties, suggests that both proteins fulfill different functions in vivo. ..