Gene Symbol: crygn2
Description: crystallin, gamma N2
Alias: crygnb, zgc:92717, gamma-crystallin N-B, gamma-D-crystallin, gamma-N-crystallin-B, gamma-N2-crystallin, gammaN2-crystallin
Wistow G, Wyatt K, David L, Gao C, Bateman O, Bernstein S, et al
. gammaN-crystallin and the evolution of the betagamma-crystallin superfamily in vertebrates. FEBS J. 2005;272:2276-91 pubmed
..Although well conserved throughout vertebrate evolution, gammaN in primates has apparently undergone major changes and possible loss of functional expression. ..
Wardle F, Odom D, Bell G, Yuan B, Danford T, Wiellette E, et al
. Zebrafish promoter microarrays identify actively transcribed embryonic genes. Genome Biol. 2006;7:R71 pubmed
..This approach will allow investigators to determine the genomic binding locations of DNA interacting proteins during development and expedite the assembly of the genetic networks that regulate embryogenesis. ..
Wages P, Horwitz J, Ding L, Corbin R, Posner M. Changes in zebrafish (Danio rerio) lens crystallin content during development. Mol Vis. 2013;19:408-17 pubmed
..Similarities with mammalian crystallin expression continue to support the use of the zebrafish as a model for lens crystallin function. ..
Gómez Requeni P, de Vareilles M, Kousoulaki K, Jordal A, Conceição L, Rønnestad I. Whole body proteome response to a dietary lysine imbalance in zebrafish Danio rerio. Comp Biochem Physiol Part D Genomics Proteomics. 2011;6:178-86 pubmed publisher
..Excess Lys was accompanied by an up-regulation of proteins related to glycolysis, steroidogenesis and sexual maturation. ..
Binelli A, Del Giacco L, Santo N, Bini L, Magni S, Parolini M, et al
. Carbon nanopowder acts as a Trojan-horse for benzo(Î±)pyrene in Danio rerio embryos. Nanotoxicology. 2017;11:371-381 pubmed publisher
..The entire dataset suggested a Trojan-horse mechanism involved in the biological impacts on Danio rerio embryos especially due to different bioaccumulation pathways and cellular targets. ..
Parolini M, Bini L, Magni S, Rizzo A, Ghilardi A, Landi C, et al
. Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos. Environ Pollut. 2018;232:603-614 pubmed publisher
..Our data confirmed the potential toxicity of low concentrations of COC, BE and EME, and helped to shed light on their MoA on an aquatic vertebrate during early developmental period. ..