Gene Symbol: cryba2a
Description: crystallin, beta A2a
Alias: zgc:86610, crystallin, beta A2a
Reis L, Tyler R, Muheisen S, Raggio V, Salviati L, Han D, et al
. Whole exome sequencing in dominant cataract identifies a new causative factor, CRYBA2, and a variety of novel alleles in known genes. Hum Genet. 2013;132:761-70 pubmed publisher
..Furthermore, these data suggest that less than half of dominant cataract can be explained by mutations in currently known genes...
Falisse E, Voisin A, Silvestre F. Impacts of triclosan exposure on zebrafish early-life stage: Toxicity and acclimation mechanisms. Aquat Toxicol. 2017;189:97-107 pubmed publisher
..This research highlighted oxidative stress and neurotoxicity as major toxicity mechanisms of TCS during development. ..
Parolini M, Bini L, Magni S, Rizzo A, Ghilardi A, Landi C, et al
. Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos. Environ Pollut. 2018;232:603-614 pubmed publisher
..Our data confirmed the potential toxicity of low concentrations of COC, BE and EME, and helped to shed light on their MoA on an aquatic vertebrate during early developmental period. ..
Lin Y, Mok H, Wu Y, Liang S, Hsiao C, Huang C, et al
. Comparative proteomics analysis of degenerative eye lenses of nocturnal rice eel and catfish as compared to diurnal zebrafish. Mol Vis. 2013;19:623-37 pubmed
French C, Erickson T, French D, Pilgrim D, Waskiewicz A. Gdf6a is required for the initiation of dorsal-ventral retinal patterning and lens development. Dev Biol. 2009;333:37-47 pubmed publisher
..Taken together, these data indicate that Gdf6a initiates dorsal retinal patterning independent of Bmp4, and regulates lens differentiation. ..
Wages P, Horwitz J, Ding L, Corbin R, Posner M. Changes in zebrafish (Danio rerio) lens crystallin content during development. Mol Vis. 2013;19:408-17 pubmed
..Similarities with mammalian crystallin expression continue to support the use of the zebrafish as a model for lens crystallin function. ..
Cortelazzo A, Pietri T, De Felice C, Leoncini S, Guerranti R, Signorini C, et al
. Proteomic analysis of the Rett syndrome experimental model mecp2Q63X mutant zebrafish. J Proteomics. 2017;154:128-133 pubmed publisher
..This non-mammalian vertebrate model of RTT strongly suggests a broad impact of Mecp2 dysfunction. ..