Genomes and Genes
Gene Symbol: cry5
Description: cryptochrome circadian clock 5
Alias: z6-4phr, z64phr, cryptochrome circadian clock 5, 6-4 photolyase, cry5/6-4phr, cryptochrome 5
- Mracek P, Santoriello C, Idda M, Pagano C, Ben Moshe Z, Gothilf Y, et al. Regulation of per and cry genes reveals a central role for the D-box enhancer in light-dependent gene expression. PLoS ONE. 2012;7:e51278 pubmed publisher..Given the existence of different photoreceptors in fish cells, our results implicate the D-box enhancer as a general convergence point for light driven signaling. ..
- Mracek P, Pagano C, Fröhlich N, Idda M, Cuesta I, López Olmeda J, et al. ERK Signaling Regulates Light-Induced Gene Expression via D-Box Enhancers in a Differential, Wavelength-Dependent Manner. PLoS ONE. 2013;8:e67858 pubmed publisher..Thus, we reveal that D-box-driven gene expression is regulated via ERK/MAPK signaling in a strongly wavelength-dependent manner. ..
- Zucchi S, Mirbahai L, Castiglioni S, Fent K. Transcriptional and physiological responses induced by binary mixtures of drospirenone and progesterone in zebrafish (Danio rerio). Environ Sci Technol. 2014;48:3523-31 pubmed publisher..Effects of DRS and P4 were additive for most of the investigated parameters and occurred at environmentally relevant concentrations. They may translate to adverse reproductive effects in fish. ..
- Osaki T, Uchida Y, Hirayama J, Nishina H. Diphenyleneiodonium chloride, an inhibitor of reduced nicotinamide adenine dinucleotide phosphate oxidase, suppresses light-dependent induction of clock and DNA repair genes in zebrafish. Biol Pharm Bull. 2011;34:1343-7 pubmed..Our findings also support the existence of a regulatory link between photoreactivation and the circadian clock in this species. ..