Gene Symbol: cry4
Description: cryptochrome circadian clock 4
Alias: fi23e01, wu:fi23e01, zcry4, cryptochrome circadian clock 4, cry3, cryptochrome 4
Kobayashi Y, Ishikawa T, Hirayama J, Daiyasu H, Kanai S, Toh H, et al
. Molecular analysis of zebrafish photolyase/cryptochrome family: two types of cryptochromes present in zebrafish. Genes Cells. 2000;5:725-38 pubmed
..The expressions of these cry genes oscillate in a circadian manner, but their patterns differ. These findings suggest that functionally diverse cry genes are present in zebrafish and each gene has different role in the molecular clock. ..
Ozturk N, Selby C, Song S, Ye R, Tan C, Kao Y, et al
. Comparative photochemistry of animal type 1 and type 4 cryptochromes. Biochemistry. 2009;48:8585-93 pubmed publisher
..degraded by a light-initiated reaction in Drosophila S2, zebrafish Z3, and human HEK293T cell lines, but zebrafish CRY4 (type 4) is not...
Liu C, Hu J, Qu C, Wang L, Huang G, Niu P, et al
. Molecular evolution and functional divergence of zebrafish (Danio rerio) cryptochrome genes. Sci Rep. 2015;5:8113 pubmed publisher
..cry1aa (zcry1a in the old nomenclature), cry1ab (zcry1b), cry1ba (zcry2a), cry1bb (zcry2b), cry2 (zcry3) and cry3 (zcry4)...
Purushothaman S, Saxena S, Meghah V, Meena Lakshmi M, Singh S, Brahmendra Swamy C, et al
. Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress. J Sleep Res. 2015;24:458-65 pubmed publisher
..It is hypothesized that the differential regulation of these genes might lead to the discovery of potential diagnostic markers for gaining insight into the light/dark-associated stress in humans. ..