Gene Symbol: crp3
Description: C-reactive protein 3
Alias: si:ch211-234p6.12, uncharacterized protein LOC100141350, PTX3
Gonçalves A, Páscoa I, Neves J, Coimbra J, Vijayan M, Rodrigues P, et al
. The inhibitory effect of environmental ammonia on Danio rerio LPS induced acute phase response. Dev Comp Immunol. 2012;36:279-88 pubmed publisher
..We hypothesize that high environmental ammonia-mediated elevation of cortisol levels in zebrafish may be playing a key role in this immunosuppression, while the mechanisms involved remains to be elucidated. ..
Falco A, Cartwright J, Wiegertjes G, Hoole D. Molecular characterization and expression analysis of two new C-reactive protein genes from common carp (Cyprinus carpio). Dev Comp Immunol. 2012;37:127-38 pubmed publisher
..It is proposed that the two carp CRP genes defined differ in their expression profiles which may suggest differences in their biological activities...
Zhao S, Xie P, Li G, Jun C, Cai Y, Xiong Q, et al
. The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR. Proteomics. 2012;12:300-12 pubmed publisher
..In conclusion, MC-RR damaged the testes and was toxic to the reproductive system of male zebrafish mainly through causing oxidative stress. ..
Chen R, Qi J, Yuan H, Wu Y, Hu W, Xia C. Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces. J Struct Biol. 2015;189:259-68 pubmed publisher
..In addition, the FcR-binding sites of hSAP are partially conserved in Dare-PTX. These results will shed light on the understanding of a primitive PTX in bony fish, which evolved approximately 450 million years ago. ..
Estepa A, Coll J. Innate Multigene Family Memories Are Implicated in the Viral-Survivor Zebrafish Phenotype. PLoS ONE. 2015;10:e0135483 pubmed publisher
..The implications of the so-called "trained immunity" for future research in this field are also discussed. ..
Bello Perez M, Falco A, Medina Gali R, Pereiro P, Encinar J, Novoa B, et al
. Neutralization of viral infectivity by zebrafish c-reactive protein isoforms. Mol Immunol. 2017;91:145-155 pubmed publisher
..These findings may help to study similar functions on the one-gene-coded human CRP, which is widely used as a clinical biomarker for bacterial infections, tissue inflammation and coronary heart diseases. ..
Yilmaz O, Patinote A, Nguyen T, Com E, Lavigne R, Pineau C, et al
. Scrambled eggs: Proteomic portraits and novel biomarkers of egg quality in zebrafish (Danio rerio). PLoS ONE. 2017;12:e0188084 pubmed publisher