Gene Symbol: crp2
Description: C-reactive protein 2
Alias: si:ch211-234p6.13, wu:fi20c07, uncharacterized protein LOC327615, PTX2
Li F, Duggal R, Oliva O, Karki S, Surolia R, Wang Z, et al
. Heme oxygenase-1 protects corexit 9500A-induced respiratory epithelial injury across species. PLoS ONE. 2015;10:e0122275 pubmed publisher
Powell M, Pegues M, Szalai A, Ghanta V, D Abramo L, Watts S. Effects of the Dietary Ï‰3:Ï‰6 Fatty Acid Ratio on Body Fat and Inflammation in Zebrafish (Danio rerio). Comp Med. 2015;65:289-94 pubmed
Lin B, Chen S, Cao Z, Lin Y, Mo D, Zhang H, et al
. Acute phase response in zebrafish upon Aeromonas salmonicida and Staphylococcus aureus infection: striking similarities and obvious differences with mammals. Mol Immunol. 2007;44:295-301 pubmed
..Our results constitute the first demonstration of a similar while different immune response in zebrafish and open new avenues for the investigation of evolutionary conserved and fish specific mechanisms of innate immunity...
Falco A, Cartwright J, Wiegertjes G, Hoole D. Molecular characterization and expression analysis of two new C-reactive protein genes from common carp (Cyprinus carpio). Dev Comp Immunol. 2012;37:127-38 pubmed publisher
..It is proposed that the two carp CRP genes defined differ in their expression profiles which may suggest differences in their biological activities...
Chen R, Qi J, Yuan H, Wu Y, Hu W, Xia C. Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces. J Struct Biol. 2015;189:259-68 pubmed publisher
..In addition, the FcR-binding sites of hSAP are partially conserved in Dare-PTX. These results will shed light on the understanding of a primitive PTX in bony fish, which evolved approximately 450 million years ago. ..
Estepa A, Coll J. Innate Multigene Family Memories Are Implicated in the Viral-Survivor Zebrafish Phenotype. PLoS ONE. 2015;10:e0135483 pubmed publisher
..The implications of the so-called "trained immunity" for future research in this field are also discussed. ..
Bello Perez M, Falco A, Medina Gali R, Pereiro P, Encinar J, Novoa B, et al
. Neutralization of viral infectivity by zebrafish c-reactive protein isoforms. Mol Immunol. 2017;91:145-155 pubmed publisher
..As shown by microarray hybridization and proteomic techniques, crp2/CRP2 and crp5/CRP5 transcripts/proteins were among the most modulated during in vivo viral infection situations ..