cnbpb

Summary

Gene Symbol: cnbpb
Description: CCHC-type zinc finger, nucleic acid binding protein b
Alias: cnbp, wu:fj34c03, zinc finger protein 9
Species: zebrafish

Top Publications

  1. Margarit E, Armas P, García Siburu N, Calcaterra N. CNBP modulates the transcription of Wnt signaling pathway components. Biochim Biophys Acta. 2014;1839:1151-60 pubmed publisher
    Cellular nucleic acid binding protein (CNBP) is a small and highly conserved protein with nucleic acid chaperone activity that binds single-stranded nucleic acids...
  2. de Peralta M, Mouguelar V, Sdrigotti M, Ishiy F, Fanganiello R, Passos Bueno M, et al. Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes. Cell Death Dis. 2016;7:e2397 pubmed publisher
    ..On the other hand, Treacle depletion led to a lowering in the abundance of Cnbp, a protein required for proper craniofacial development...
  3. B hne A, Darras A, D Cotta H, Baroiller J, Galiana Arnoux D, Volff J. The vertebrate makorin ubiquitin ligase gene family has been shaped by large-scale duplication and retroposition from an ancestral gonad-specific, maternal-effect gene. BMC Genomics. 2010;11:721 pubmed publisher
    ..Comparative expression analysis strongly suggests that the ancestral E3 ubiquitin ligase function of the single copy mkrn gene before duplication in vertebrates was gonad-specific, with maternal expression in early embryos...
  4. Weiner A, Sdrigotti M, Kelsh R, Calcaterra N. Deciphering the cellular and molecular roles of cellular nucleic acid binding protein during cranial neural crest development. Dev Growth Differ. 2011;53:934-47 pubmed publisher
    Cellular nucleic acid binding protein (Cnbp) is a highly conserved single-stranded nucleic acid binding protein required for rostral head development...
  5. Armas P, Margarit E, Mouguelar V, Allende M, Calcaterra N. Beyond the binding site: in vivo identification of tbx2, smarca5 and wnt5b as molecular targets of CNBP during embryonic development. PLoS ONE. 2013;8:e63234 pubmed publisher
    b>CNBP is a nucleic acid chaperone implicated in vertebrate craniofacial development, as well as in myotonic dystrophy type 2 (DM2) and sporadic inclusion body myositis (sIBM) human muscle diseases...