cldnj

Summary

Gene Symbol: cldnj
Description: claudin j
Alias: fc30g01, wu:fc30g01, claudin j
Species: zebrafish

Top Publications

  1. Hardison A, Lichten L, Banerjee Basu S, Becker T, Burgess S. The zebrafish gene claudinj is essential for normal ear function and important for the formation of the otoliths. Mech Dev. 2005;122:949-58 pubmed
    ..Antisense in situ hybridization to the cldnj gene showed expression first in the otic placode and later asymmetric expression in the otic vesicle...
  2. Clelland E, Kelly S. Tight junction proteins in zebrafish ovarian follicles: stage specific mRNA abundance and response to 17beta-estradiol, human chorionic gonadotropin, and maturation inducing hormone. Gen Comp Endocrinol. 2010;168:388-400 pubmed publisher
    ..The data supports a role for the endocrine regulation of TJ proteins in ovarian follicle development. ..
  3. Han Y, Mu Y, Li X, Xu P, Tong J, Liu Z, et al. Grhl2 deficiency impairs otic development and hearing ability in a zebrafish model of the progressive dominant hearing loss DFNA28. Hum Mol Genet. 2011;20:3213-26 pubmed publisher
    ..Thus, this work reveals an evolutionarily conserved function of Grhl2 in otic development and provides a fish model for further studying mechanisms of Grhl2-related hearing loss...
  4. Loh Y, Christoffels A, Brenner S, Hunziker W, Venkatesh B. Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes. Genome Res. 2004;14:1248-57 pubmed
  5. Kumai Y, Bahubeshi A, Steele S, Perry S. Strategies for maintaining Na? balance in zebrafish (Danio rerio) during prolonged exposure to acidic water. Comp Biochem Physiol A Mol Integr Physiol. 2011;160:52-62 pubmed publisher
    ..These results demonstrate that in acidic water, zebrafish maintain their whole body Na? balance primarily by regulating Na? uptake, rather than Na? efflux. ..
  6. Li I, Chan C, Lu Y, Wu Y, Chen Y, Li G, et al. Zebrafish kr├╝ppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages. PLoS ONE. 2011;6:e20974 pubmed publisher
    ..Moreover, the regulation of differentiation of goblet cells in zebrafish intestine by Notch signaling at least partially mediated through Klf4a. ..