Gene Symbol: celsr3
Description: cadherin, EGF LAG seven-pass G-type receptor 3
Alias: cadherin EGF LAG seven-pass G-type receptor 3
Species: zebrafish

Top Publications

  1. Wada H, Tanaka H, Nakayama S, Iwasaki M, Okamoto H. Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain. Development. 2006;133:4749-59 pubmed
    ..e. preventing integration of differentiated neurons into the neuroepithelial layer). This contrasts markedly with their reported role in reintegration of neuroepithelial daughter cells into the neuroepithelial layer after cell division. ..
  2. Cui S, Capecci L, Matthews R. Disruption of planar cell polarity activity leads to developmental biliary defects. Dev Biol. 2011;351:229-41 pubmed publisher
    ..Our results demonstrate that PCP plays an important role in vertebrate biliary development, interacting with other factors known to be involved in biliary morphogenesis. ..
  3. Lewis A, Wilson N, Stearns G, Johnson N, Nelson R, Brockerhoff S. Celsr3 is required for normal development of GABA circuits in the inner retina. PLoS Genet. 2011;7:e1002239 pubmed publisher
    ..Here we report a newly identified zebrafish mutant in which the absence of the atypical cadherin, Celsr3, leads to a specific defect in the development of GABAergic signaling in the inner retina...
  4. Lewis A, Mahoney J, Wilson N, Brockerhoff S. Identification of amacrine subtypes that express the atypical cadherin celsr3. Exp Eye Res. 2015;130:51-7 pubmed publisher
    We previously identified Celsr3, an atypical cadherin, as essential for normal inhibitory circuit formation in the inner retina...