Gene Symbol: celsr2
Description: cadherin, EGF LAG seven-pass G-type receptor 2
Alias: celsr2l, fmi2, off-road, ord, si:rp71-11b17.1, si:rp71-11b17.9, cadherin EGF LAG seven-pass G-type receptor 2
Species: zebrafish

Top Publications

  1. Wada H, Tanaka H, Nakayama S, Iwasaki M, Okamoto H. Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain. Development. 2006;133:4749-59 pubmed
    ..Here, we show that expression of the off-limits/frizzled3a (olt/fz3a) and off-road/celsr2 (ord/celsr2) genes in neuroepithelial cells maintains the facial (nVII) motor neurons near the pial surface during ..
  2. Lewis A, Wilson N, Stearns G, Johnson N, Nelson R, Brockerhoff S. Celsr3 is required for normal development of GABA circuits in the inner retina. PLoS Genet. 2011;7:e1002239 pubmed publisher
    ..These findings support the previously postulated inner retina origin for the b1 component and reveal a new role for Celsr3 in the normal development of ON visual pathway circuitry in the inner retina. ..
  3. Bjarnadóttir T, Fredriksson R, Schioth H. The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors. Gene. 2005;362:70-84 pubmed
    ..This report provides a comprehensive overview of the expansion/deletions of the groups within the Glutamate receptor family. ..
  4. Witzel S, Zimyanin V, Carreira Barbosa F, Tada M, Heisenberg C. Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. J Cell Biol. 2006;175:791-802 pubmed
    ..We propose that Wnt11, by interacting with Frizzled 7 and Flamingo, modulates local cell contact persistence to coordinate cell movements during gastrulation...
  5. Carreira Barbosa F, Kajita M, Kajita M, Morel V, Wada H, Okamoto H, et al. Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development. 2009;136:383-92 pubmed publisher
    ..Fmi/Celsr therefore has a dual role in mediating two separate morphogenetic movements through its roles in mediating cell cohesion and Wnt/PCP signalling during zebrafish gastrulation. ..
  6. Cui S, Capecci L, Matthews R. Disruption of planar cell polarity activity leads to developmental biliary defects. Dev Biol. 2011;351:229-41 pubmed publisher
    ..Our results demonstrate that PCP plays an important role in vertebrate biliary development, interacting with other factors known to be involved in biliary morphogenesis. ..