Gene Symbol: ccnf
Description: cyclin F
Alias: cb443, zgc:77240, cyclin-F
Species: zebrafish

Top Publications

  1. Newman M, Tucker B, Nornes S, Ward A, Lardelli M. Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis. J Alzheimers Dis. 2009;16:133-47 pubmed publisher
    ..Decreased ccng1 expression does not rescue the hydrocephalus or pigmentation phenotypes of embryos with aberrant splicing of psen1 exon 8. ..
  2. Hogan A, Don E, Rayner S, Lee A, Laird A, Watchon M, et al. Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype. Hum Mol Genet. 2017;26:2616-2626 pubmed publisher
    ..ALS-linked mutations in CCNF were recently reported, however the pathogenic mechanisms associated with these mutations are yet to be established...